Director of the Ined-Inserm-EFS of Elfe Unit and Inserm research director
01 45 59 51 05
Insight on the preliminary findings of the Elfe study, by Marie-Aline Charles,
Research director of Inserm Unit 1018 “Centre for Research in Epidemiology and Population Health”
Elfe study director (Ined-Inserm-EFS combined unit)
In the health field, the survey showed that 70 % of mothers breastfeed, a number that has significantly grown since the 1970’s2:
Although infant formula is a completely acceptable alternative today for mothers who do not want to or cannot breastfeed, a considerable amount of scientific research shows that breastfeeding has a positive effect on the health of the mother and child. The findings of this Elfe study confirm that there has been an increasing trend documented over the last several years to initiate breastfeeding in the maternity ward, in conjunction with numerous public health initiatives that were started to promote breastfeeding.
To continue efforts to promote breastfeeding, researchers suggest involving fathers as much as possible while allowing more women to attend childbirth classes (for example, 70% of those in the working class did not attend a class, compared to 27% of those in the managerial/professional class).
In the field of environmental health, the preliminary findings on housing contamination by micro-organisms are going to be published3:
3,000 dust collectors were placed in children’s rooms for the first two months of their life, and the micro-organisms collected (mites, mold, etc.) were analysed to evaluate their influence on future health, particularly respiratory health. Six different housing contamination profiles were identified, of which two were commonly found in Western France (one had high numbers of mites and bacteria, and the other had mites, bacteria and mold). A higher humidity rate and temperatures more conducive to the growth of these micro-organisms could explain these results. The geographic breakdown of these profiles overlaps with the breakdown from a recent study conducted in day care nurseries on the frequency of asthma in young children . The follow-up data from the Elfe children will help confirm whether or not there is a relationship between these contamination profiles and children’s respiratory health. The objective within the Elfe study is to observe the respiratory diseases in these regions more carefully in correlation with the quality of housing, ventilation, isolation, etc.
The next publications in the field of social sciences will provide information on how parents prepare for the birth of a child, and in particular their desire to find out the baby’s gender5: :
The Elfe results show that nearly nine future parents out of ten want to know the gender of their child before his/her birth. For their first child, 60% of parents have no preference. When they do have a preference, it is equal for mothers (20 % for a girl and 20% for a boy), while fathers favour boys (25% would prefer a boy and 14% a girl). When it is a second child, the proportion of parents who do not have a preference decreases slightly. And when they do have a preference, it depends greatly on the gender of the oldest child; parents often want mixed-gender siblings. One of this research project’s objectives is to measure if this preference influences the beginning of parenthood.
A new survey when the child is three and a half and entering preschool
Two contacts are planned during this important stage young children’s lives:
• A telephone interview with one of the parents will focus primarily on updating information about the child’s environment (family, social, economic, culture, diet, etc.), the parents’ child-rearing practices, the child’s psychomotor development and health events. New topics including entry into preschool will also be discussed.
• A home visit with approximately 10,000 families, which will provide direct contact with the child. Researchers will use drawing, visual games and image association to gather information about the child’s cognitive development and learning.
Video – Survey home visit (French version)
For families who have already participated in the lab work component in the maternity ward, new non-invasive sample collections, such as a urine sample from the child, are scheduled. Dust will also be collected in a few households to measure the substances found in the children’s environment. Finally, volunteer families can have their child wear a “movement counter” or accelerometer to measure their physical activity and sleep quality.
The progress of this unprecedented study, which includes one child out of 50 of the births in France in 2011, is based on the involvement of families who agreed to an initial interview in the maternity ward and then regular follow-up. The Elfe study families are playing a vital role in research for 20 years!
1 Elfe is the first French longitudinal study dedicated to monitoring children from birth to adulthood. It takes a look at childhood from the multiple perspectives of social science, health and environmental health in order to better understand the interaction between them. During four enrolment periods in 2011, more than 18,000 families agreed to take part in this Elfe adventure in metropolitan France.
2 BEH no. 27 from 07 October 2014, Prevalence of breastfeeding based on parent characteristics and delivery conditions. Results from the Elfe maternity survey, Metropolitan France, 2011, by Claire Kersuzan and coll., Institut national de la recherche agronomique (Inra – National Institute of Agronomic Research) (French version)
3 Steffi Rocchi, Gabriel Reboux and coll., Université de Franche Comté, UMR 6249 Chrono-environnement, publication to appear in Sciences of total Environment under the title: Microbiological characterization of 3193 French dwellings of Elfe cohort children.
4 Study conducted with 20,000 children in day care nurseries who presented with wheezing and asthma: Delmas MC, Prevalence and controlling asthma in young children, Revue des maladies respiratoires, 2012.
5 XVIIIe Aidelf international conference, Université de Bari, 26-30 May 2014, Olivia Samuel and coll., Université Versailles St Quentin, Spring/Ined-IPOPs
A team led by Prof. Marina Cavazzana, working at Necker Hospital for Sick Children, AP-HP, and the Imagine Institute (AP-HP/Inserm/Paris Descartes University) performed gene therapy on a 13-year-old patient with severe sickle cell anaemia in October 2014 as part of a phase ...
A veritable sensor: a team of Inserm and CNRS researchers at the Institute of Pharmacology and Structural Biology (IPBS, CNRS/Paul Sabatier University – Toulouse III) has identified a protein that is able to detect various allergens in the respiratory tract, which are ...
About the Elfe study