- 2021
- Press releases - 21.09.2021
Covid-19 : identification de cellules immunitaires associées à la survie dans les formes sévères de la maladie
Since the pandemic began, many studies have tried to explain what differentiates the immune response of people with severe forms of COVID-19 resulting in death from that of other patients. In a new study, researchers from Inserm and Sorbonne Université at the Center for Immunology and Infectious Diseases, in collaboration with physician researchers from Paris hospitals group AP-HP, focused on a type of immune response known as the cellular immune response.
- Press releases - 20.09.2021
Absence d’efficacité du remdesivir chez les patients hospitalisés atteints de Covid-19 et poursuite de l’essai DisCoVeRy pour tester un nouveau médicament antiviral
The Discovery clinical trial was initially launched in France by Inserm in March 2020, to evaluate several possible treatments for COVID-19. Its European expansion was made possible by the EU-RESPONSE project, funded by the European Commission. Interim analysis of the trial data had led to the recommendation to suspend the recruitment of remdesivir group patients for futility – that is to say due to the very low likelihood of this treatment showing a benefit, even if inclusions were continued.
- Press releases - 16.09.2021
Covid-19 : les confinements ont eu un impact délétère sur la sévérité du cancer colorectal métastatique
La pandémie de Covid-19 a très fortement fragilisé la lutte globale contre le cancer. Les confinements successifs ont limité l’accès au soin et ont conduit à une réduction significative du dépistage, du diagnostic et de l’orientation vers les hôpitaux des patients atteints de cancer.
- Press releases - 16.09.2021
COVID-19: Discovery of a Molecular Signature of Pediatric Myocarditis
Researchers, doctors and teacher-researchers analyzed blood samples from a cohort of 56 pediatric patients admitted to Hôpital Necker Enfants-Malades AP-HP. What they saw was the abnormal expression of several genes associated with the development of severe forms of myocarditis.
- Press releases - 10.09.2021
Demonstration of the major role of mutations in the PIK3CA gene in sporadic cavernomas
Teams from Inserm, CNRS, AP-HP and Sorbonne University, grouped together within the Brain Institute at Pitié-Salpêtrière AP-HP hospital and coordinated by Dr Matthieu Peyre and Prof. Michel Kalamarides, studied the presence of mutations in the PIK3CA genes in cavernomas.
- Press releases - 11.08.2021
ComPaRe study: one in twelve patients hesitant to be vaccinated changes their mind after consulting information on the benefits and risks of vaccines
A team of researchers has developed an online tool for viewing the benefits and the risks of vaccination against Covid-19. Convincing the hesitant population to get vaccinated is a matter of major concern in the fight against the Covid-19 epidemic. The main reasons for refusing vaccination are concern and demand for further hindsight regarding the safety and efficacy of vaccines.
- Press releases - 09.08.2021
Vaccination Covid-19 et populations particulières : une grande étude de cohorte pour orienter les recommandations destinées aux plus fragiles
La cohorte ANRS COV-POPART – « cohorte vaccinale Covid-19 des populations particulières » – a été conçue pour évaluer la réponse immunitaire induite par les vaccins contre la Covid-19 au sein de différents groupes de personnes suivies pour une maladie chronique comparativement à des personnes en bonne santé.
- Press releases - 03.08.2021
The appendix is not an unnecessary organ but is in fact correlated with a longer lifespan
Long considered an unnecessary organ, the appendix is now the focus of several studies that aim to better understand its role. Present in many mammals, including humans, it appears to have developed at least 16 times over the course of the evolutionary history of mammals, suggesting that its function must confer a positive selective advantage on those that have it.
- Press releases - 02.08.2021
Diabetes: Study Of Satiety Mechanism Yields New Knowledge
To increase their understanding of the disease, a team of researchers has for several years studied the role of leptin, a hormone involved in appetite control that sends satiety signals to the brain.
- Press releases - 27.07.2021
Suspension provisoire des travaux sur les prions dans les laboratoires de recherche publics français
Les directions générales de l’ANSES, du CEA, du CNRS, d’INRAE et de l’Inserm, ont décidé conjointement et en accord avec le ministère de l’enseignement supérieur, de la recherche et de l’innovation de suspendre à titre conservatoire l’ensemble de leurs travaux de recherche et d’expérimentation relatifs aux maladies à prions, pour une durée de trois mois.