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Bronchopneumopathie chronique obstructive : une mutation génétique confirmée comme facteur de prédisposition

06 Dec 2021 | By INSERM (Newsroom) | Public health

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An innate contribution of human nicotinic receptor polymorphisms to COPD-like lesions, Nature Communications, 4 novembre 2021

Julie Routhier1, Stéphanie Pons2, Mohamed Lamine Freidja1,8, Véronique Dalstein1,3, Jérôme Cutrona1, Antoine Jonquet1, Nathalie Lalun1, Jean-Claude Mérol1,4, Mark Lathrop5, Jerry A. Stitzel6, Gwenola Kervoaze7, Muriel Pichavant7, Philippe Gosset7, Jean-Marie Tournier1, Philippe Birembaut1,3,9, Valérian Dormoy1,9, Uwe Maskos2,9

1 Université de Reims Champagne-Ardenne, Inserm, P3Cell UMR-S1250 Reims, France.
2 Institut Pasteur, Université de Paris, Integrative Neurobiology of Cholinergic Systems, CNRS UMR 3571 Paris, France.
3 Department of Biopathology, CHU of Reims, Reims, France.
4 Department of Otorhinolaryngology, CHU of Reims, Reims, France.
5 McGill University Genome Center, Montréal, QC, Canada.
6 Institute for Behavioral Genetics, University of Colorado, Boulder, CO, USA.
7 University of Lille, CNRS UMR9017, Inserm U1019, CHU Lille, Institut Pasteur de Lille, CIIL – Center for Infection and Immunity of Lille, Lille, France.
8 Present address: Department of Biochemistry and Microbiology, Faculty of Sciences, University of M’sila, M’sila, Algeria.
9 These authors contributed equally: Philippe Birembaut, Valérian Dormoy, Uwe Maskos.

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