Category Archives: Health technologies

Repurposing Drugs to Fight the Flu: a Phase 2 Clinical Trial for FLUNEXT

L’équipe VirPath du CIRI, en collaboration avec le laboratoire du Dr Guy Boivin (chaire de recherche du Canada sur les virus émergents, a développé et validé une stratégie innovante qui consiste à identifier et exploiter directement des échantillons infectieux prélevés cliniquement, afin de sélectionner et d’utiliser des médicaments déjà commercialisés pour soigner d’autres virus (on parle alors de « repositionnement de médicaments »). Ce programme a été financé par l’Inserm, la DGOS, l’Agence National de la Recherche, la Région Auvergne Rhône-Alpes, l’Université Claude Bernard et l’Université Laval.

A patient has been living with an artificial larynx for the 18 months

In 2013, researchers from Inserm and physicians from the Strasbourg University Hospitals announced their success in developing an artificial larynx. Since the first time they began implanting this prosthesis five years ago in patients whose own larynx had been removed for health reasons, they have optimized both the implant and their surgical technique. Today, they are presenting the case of a patient who has had the implant for 18 months, a feat that has enabled him to regain his voice and sense of smell, breathe through his nose and mouth, and not have to use his tracheostomy tube.

Biological Engineering: Marine Vessels

Researchers are aiming to produce flexible and malleable substitute materials to replace defective small blood vessels. The team led by Didier Letourneur, in Inserm Unit 1148, took inspiration from the composition of algae when designing polysaccharide-based vessels.

Looking at the brain to prevent depression in adolescents

Depression is a real public health issue with 8% of adolescents affected by it, according to the French National Authority for Health (HAS). Adolescence is a time of transition during which young people are prone to episodes of depression. This often complicates the diagnosis of this disease.

Coffee colour…

Inserm researchers at I-Stem (Institute for Stem Cell Therapy and Exploration of Monogenic diseases) have developed a model reproducing in vitro the hyperpigmentation associated with neurofibromatosis type 1 from embryonic stem cells carrying the mutation responsible for this disease.

An atlas of human brain connections !

One of the major challenges of modern neuroscience is to define the complex pattern of neural connections that underlie cognition and behaviour.

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