Category Archives: Neurosciences, cognitives sciences, neurology and psychiatry

Treating depressive symptoms from their roots

A wide range of compounds is on the market to ameliorate depressive symptoms, however their efficiency is achieved only after long periods of treatment and not in 100% of patients.

Looking at the brain to prevent depression in adolescents

Depression is a real public health issue with 8% of adolescents affected by it, according to the French National Authority for Health (HAS). Adolescence is a time of transition during which young people are prone to episodes of depression. This often complicates the diagnosis of this disease.

Discovery of a new mechanism of action of a protein that is toxic in Parkinson’s disease

A team coordinated by Antoine Triller has just identified the target of an alpha-synuclein protein, which is pathogenic in Parkinson’s disease.

Observing the brain of moving animals

Two teams led by Ivan Cohen and Mickaël Tanter have improved the fUS method to make it portable and usable with conscious and mobile rats at the same time as an EEG.

Using Google Trends for suicide prevention?

Google Trends might be used to follow not only the spread of infectious epidemics, but that of other phenomena as well, such as suicide epidemics. This hypothesis led psychiatrist and researcher Guillaume Fond and his team to study in greater detail the relationship between the number of Google searches for terms such as suicide, depression and bipolar disorder and the risk of a suicide “epidemic.”

Glucose to help blindness

The loss of cones, those photoreceptors located in the retina, is the major cause of disability for people with inherited retinal degeneration. Preventing their loss would prevent more than a million people worldwide from becoming blind.

Drug abuse and depression: towards a new understanding of brain mechanisms

Withdrawal, experienced by people when they stop using addictive drugs such as cocaine, induces states of anxiety and depression. This process makes the individual want to take the substance again, and thus plays a role in the establishment of drug addiction. The depressive syndrome thus represents an additional obstacle to be overcome when addicts are being weaned off drugs.

When breathing frees our mind

These results show the automatic (brain stem) and voluntary (cortex) breathing mechanisms in a new light, and provide us with information on the cognitive impact associated with voluntary breathing.

Tactile exploration decoded

souris blanches et noires

Precisely how do we distinguish the texture of objects by touch? This is what has just been decoded by a study led by Clément Léna, research director at Inserm and Daniela Popa, a researcher at Inserm in Mixed Research Unit 1024: Biology Institute, École Normale Supérieure (Inserm, ENS, CNRS) and published in the journal Nature Neuroscience. Interactions between several regions of the brain that have until now not been identified are responsible for adjusting movement and refining our sense of touch.

L-Dopa treatment alleviates sleep disturbances associated with Parkinson’s disease

INSERM researchers working under the guidance of Chantal François (INSERM Unit 1127 /Institut du cerveau et de la moelle épinière/Université Pierre et Marie-Curie/AP-HP) have now been able to record and measure over extended periods of time, using a miniature device, the quality of sleep in animals suffering from Parkinson’s disease. The study shows that a pure dopaminergic lesion gives rise to sleep disturbances, and that treatment using L-Dopa leads to significant improvement.

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