Category Archives: Neurosciences, cognitives sciences, neurology and psychiatry

New risk factors for alcohol abuse in adolescents brought to light

An international team involving researchers from INSERM, CEA and APHP in France have successfully modelled the risk factors for alcohol abuse during adolescence. The results of the study were published on Nature Magazine’s website on 2 July.

Identification of the neuronal network that controls our actions and errors

Identification of the neuronal network that controls our actions and errors

The satiety mechanism described and restored in mice

Leptin is a hormone secreted by adipose cells, sending the satiety signal to the brain. Sometimes, certain overweight or obese individuals develop resistance to this hormone, which is no longer able to deliver its message.

Escaping the adverse effects of morphine

Despite its beneficial effects against pain, morphine use is accompanied by adverse effects such as constipation, nausea, vomiting, respiratory depression, and potential dependence on the drug. A research team led by Alain Eschalier, Director of Inserm Unit 1107, Neuro-Dol, in Clermont Ferrand, has just shown that it is possible to separate these two types of effects, and retain the desired analgesic effect without the adverse effects.

A disrupted biological clock: a risk factor for anxiety disorders

In mammals, light is essential in order for the body to function properly. This response to light is controlled in our bodies by a biological clock. Like well-oiled clockwork, the central clock located in a small structure of the brain known as the hypothalamus in turn synchronises numerous secondary clocks present in other areas of the brain, and in some peripheral organs. These clocks control the expression of many genes that allow the body to adapt to the environment on a daily basis.

Collaboration ou concurrence : que se passe-t-il dans notre cerveau ?

Au bureau ou lors de la pratique d’un sport, vous avez surement été confronté à des situations de compétition ou au contraire des situations de collaboration, vous demandant d’atteindre un même objectif à plusieurs. S’il s’agit d’un objectif commun, nous avons tendance à diminuer notre effort personnel, et ce d’autant plus que le groupe est nombreux. A l’inverse dans un contexte de compétition, l’homme aura tendance à fournir un effort plus important, pour creuser l’écart avec ses concurrents.

Prevention of risk of sudden death in epilepsy

Sudden unexpected death in epilepsy (SUDEP) is one of the most frequent causes of sudden non-accidental death in young adults. The origin of SUDEP remains unknown, since it generally occurs at night, unwitnessed.

Multiple sclerosis: a composite treatment to repair damaged nerve fibres

Schéma fonctionnement sclérose en plaques

A team of researchers led by Brahim Nait Oumesmar, Inserm Research Director at the PITIE-SALPETRIERE NEUROSCIENCES RESEARCH CENTER (CRICM) in collaboration with the University of Luxembourg, has just discovered a new molecule capable of stimulating the repair of the myelin destroyed in experimental models of multiple sclerosis.

Migraine to the Tip of the Genes

Un consortium international vient de révéler 5 nouvelles régions génétiques associées à la migraine dans une étude publiée le 23 juin 2013 dans la revue Nature Genetics.

Genetic involvement in epilepsy?

Un gène impliqué dans les épilepsies dites “focales”, les plus fréquentes d’entre elles, a été découvert par l’équipe de recherche dirigée par Eric Leguern et Stéphanie Baulac de l’unité Inserm 975 « Génétique et physiopathologie des épilepsies familiales » à l’Institut du Cerveau et de la Moelle (ICM).

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