Category Archives: News in brief

Breathe…inhale…run

Onze athlètes non-asthmatiques présentant de hautes capacités d’endurance ont été recrutés pour comparer en double-aveugle deux niveaux de dose de salbutamol (200 et 800 µg) administrés par inhalation contre un placebo avant un test d’effort des muscles de la jambe.

Spermatozoa losing speed

Fecondation

L’infertilité concerne environ de 7 à 12% des couples dans le monde. Parmi les causes de l’infertilité masculine, il existe plusieurs défauts du sperme dont l’asthénozoospermie. Il s’agit une déficience de la mobilité des spermatozoides, essentielle à la rencontre des cellules sexuelles lors de la reproduction.

Genetic involvement in epilepsy?

Un gène impliqué dans les épilepsies dites “focales”, les plus fréquentes d’entre elles, a été découvert par l’équipe de recherche dirigée par Eric Leguern et Stéphanie Baulac de l’unité Inserm 975 « Génétique et physiopathologie des épilepsies familiales » à l’Institut du Cerveau et de la Moelle (ICM).

HTAP: discovery of a genetic market associated with increased risk

A genetic marker localised on chromosome 18 is associated with a doubling of the risk of pulmonary arterial hypertension (PAH).

Genetic mutation and the prognosis for renal polycystosis

The team headed by Claude Férec, director of Inserm unit in Brest, published results in the Journal of the American Society of Nephrologyfrom a cohort of 700 patients suffering from Autosomal Dominant Polycystic Kidney Disease (ADPKD)

NanoAthero: using nanomedicine to treat cardiovascular diseases

Sixteen partners from 10 European countries got together to create the “Nanomedicine for Atherosclerosis” consortium. Its aim is to study and develop the clinical feasibility of nanomedicine for targeted diagnosis and treatment of atherosclerosis.

Advances in Friedreich’s Ataxia

Friedreich’s ataxia is a rare, serious and developing neurodegenerative condition that emerges at adolescence. Those affected suffer from difficulties in coordinating voluntary movements (ataxia).

A mother’s exposure to atmospheric pollution results in a risk of her baby having low birth weight

This study, of which the French section was assigned to Rémy Slama and Johanna Lepeule, researchers at the INSERM U823 Unit, the Centre de recherche Institut Albert Bonniot, was published on 6 February 2013 in the journal entitled Environmental Health Perspectives.

Food quality and recurrent episodes of depression

Depression is a common multifactorial condition in which the appearance of symptoms is often linked to patients’ lifestyle. Of these factors, nutrition appears to play a significant role. Studies performed in a collaborative project between INSERM researchers in Montpellier and at University College London suggest than an improvement in the quality of nutrition is associated with a reduction in the recurrence of episodes of depression, particularly in women.

How does the brain decide when one needs to take a break

Before we start to exert ourselves, our brain decides to assess the situation, evaluating the cost involved and the benefits that can be derived from it. One question has not been properly explored, namely, how does the brain decide when it is time to take a break, during a period when it is involved in strenuous activity?

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