Category Archives: News in brief

Apparent age of the elderly : a diagnostic tool for primary care physicians?

To estimate the health of their elderly patients, healthcare professionals have various clinical tools at their disposal: geriatric assessment scales, health questionnaires and frailty scores. However, although these tests are appropriate to a medical context, they are more difficult for primary care physicians (PCPs) to implement because they require time and equipment that they do not necessarily possess. When evaluating the general health of an elderly patient, the PCP will first go on their detailed knowledge of him or her as well as the various signs observed during the consultation (physical appearance, gait, etc.).

Repurposing Drugs to Fight the Flu: a Phase 2 Clinical Trial for FLUNEXT

L’équipe VirPath du CIRI, en collaboration avec le laboratoire du Dr Guy Boivin (chaire de recherche du Canada sur les virus émergents, a développé et validé une stratégie innovante qui consiste à identifier et exploiter directement des échantillons infectieux prélevés cliniquement, afin de sélectionner et d’utiliser des médicaments déjà commercialisés pour soigner d’autres virus (on parle alors de « repositionnement de médicaments »). Ce programme a été financé par l’Inserm, la DGOS, l’Agence National de la Recherche, la Région Auvergne Rhône-Alpes, l’Université Claude Bernard et l’Université Laval.

What is the Origin of Human Social Intelligence?

In humans, “Theory of Mind” is the ability to understand others’ mental states: what they think, what they feel, what they desire, what they love, etc. It plays a major role in human social interactions.

Drug overconsumption in pregnant women in France

Pregnancy is a sensitive time, particularly in the first months. Pregnant women are therefore strongly advised to limit their use of medicines, as some of their effects are yet poorly known. Nevertheless, a recent study conducted by Inserm researchers reveals that pregnant French women are among the largest consumers of drugs worldwide with around ten medicines prescribed during pregnancy. A rate which remained stable throughout the period analyzed (2011-2014).

Benefits of Unit-Dose Antibiotic Sale

Between November 2014 and November 2015, a study conducted by Inserm (Unit 912 SESSTIM – Economic and Social Sciences, Health Systems and Medical Informatics), Université Aix-Marseille, IRD, CNRS and the PACA Regional Health Observatory, trialed the unit-dose dispensing of certain antibiotics across four regions in France. Out of 100 volunteer pharmacies, 75 pharmacies were randomly selected to offer unit-dose dispensing of treatment to patients with a prescription stating one or more of the 14 antibiotics concerned. The results of this trial, published in PLos ONE on September 19, 2017, are as follows:

Is Our Stubbornness Caused by Confirmation Bias?

The way in which people make decisions can sometimes seem reckless or even totally irrational. One explanation for this behavior is that humans tend to prefer information that confirms their beliefs and overlook that which contradicts them. This is a phenomenon called confirmation bias.

Osteoarthritis and metabolic disease: a “joint” therapeutic target?

Pour la première fois, des chercheurs du laboratoire de recherche « Ingénierie moléculaire et physiopathologie articulaire » (Cnrs/Université de Lorraine) et du laboratoire « Défaillances cardiovasculaires aiguë et chronique » (Inserm/Université de Lorraine) à Nancy, ont décrit le développement spontané de ce type d’arthropathie dégénérative dans un modèle murin de SMet.

MS : using MRI to predict relapse

Multiple sclerosis (MS) is an autoimmune inflammatory disease of the central nervous system. It generally affects young people, in whom it is the leading cause of non-traumatic motor disability. This disability develops either progressively or in the form of relapses interspersed with periods of remission.

Malaria: new insights into the mechanisms of parasite entry into liver cells

Malaria remains a major cause of mortality in the world, especially in Africa. The disease is caused by Plasmodium parasites, which are transmitted by mosquitoes.

Depression, cardiovascular risk… and the class struggle

Classes sociales

Depression is not just one of the world’s most incapacitating illnesses – it also comes with an increased risk of cardiovascular disease, particularly that of the coronary arteries (angina and heart attack).

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