Category Archives: Circulation, metabolism, nutrition

Pour la première fois, des chercheurs du laboratoire de recherche « Ingénierie moléculaire et physiopathologie articulaire » (Cnrs/Université de Lorraine) et du laboratoire « Défaillances cardiovasculaires aiguë et chronique » (Inserm/Université de Lorraine) à Nancy, ont décrit le développement spontané de ce type d’arthropathie dégénérative dans un modèle murin de SMet.

POMC (proopiomelanocortin) deficiency obesity is an orphan disease which has been described in 50 patients to date, although it is estimated to affect 100–500 people worldwide. Although there is currently no specific treatment, a publication in NEJM reports promising results from a phase 2 clinical trial that led to considerable weight loss in female patients.

A new study published in the journal Blood shows that red blood cells can turn against blood vessels by releasing aggressive fragments that contribute to the development of cardiovascular disease.

Dans un travail publié en ligne dans la revue Alzheimer’s & Dementia, les chercheurs de l’Inserm, se sont intéressés aux relations entre l’athérosclérose et le risque de démence chez le sujet âgé.

Roméo Ricci’s team at the Institute of Genetics and Molecular and Cellular Biology has shown that, during fasting, the pancreatic beta cells do not compensate for nutrient deficiencies by the “classic” autophagy mechanism but by breaking down insulin secretory granules

In a new study published in The American Journal of Respiratory Cell and Molecular Biology, Olivier Meilhac’s team (Inserm Unit 1148, the “Laboratory for Vascular Translational Science,” in collaboration with Inserm Unit 1152, “Physiopathology and Epidemiology of Respiratory Diseases”) addressed the transport capability of HDLs (high density lipoproteins, commonly known as “good cholesterol”)

In reality, the cholesterol levels are the result of a balance in the human body between “good” (HDL) cholesterol and “bad” (LDL) cholesterol.