Category Archives: Cancer

Les métastases au fil du sang

Imagerie de billes fluorescentes sont filmées à très haute vitesse,

Les cellules tumorales circulantes utilisent les réseaux lymphatiques et sanguins pour se disséminer dans l’organisme et former des métastases à distance de la tumeur primaire. Jacky Goetz, chercheur Inserm, et son équipe ont contribué à montrer que les propriétés des flux de ces liquides biologiques influent énormément sur le risque d’apparition de ces métastases. Ils ont notamment observé que le ralentissement du flux sanguin au niveau de la ramification des artères permettait aux cellules cancéreuses de s’accrocher à la paroi vasculaire et de s’extraire des vaisseaux pour aller coloniser les tissus.

Also posted in Press releases, Circulation, metabolism, nutrition | Tagged | Comments closed

Towards a Drug to Combat a Severe Intestinal Disease in Children, Immunocompromised Patients

Researchers have recently discovered a new candidate drug to control cryptosporidiosis, a severe intestinal disease in children, immunocompromised patients, and young ruminants. Beyond this disease, their research represents an opportunity to discover new therapeutic avenues for related infections, such as toxoplasmosis and malaria.

Also posted in Press releases, Immunology, inflammation, infectiology and microbiology | Comments closed

A Vaccine to Overcome Immunotherapy Resistance

Researchers have shown that a commercially-available vaccine can overcome resistance to immunotherapy. Their study, published in Science Translational Medicine, shows that not only can gastroenteritis vaccines induce the immunogenic death of cancer cells in vitro, but also that combining them with immunotherapy triggers a potent anti-tumor immune response in vivo – where immunotherapy alone had failed.

Also posted in Press releases, Immunology, inflammation, infectiology and microbiology | Tagged | Comments closed

Pediatric Cancers: Why Some Forms of Leukemia Only Affect Children

Acute myeloid leukemia (AML) mainly affects children, with the prognosis often being poor despite several decades of research into more effective treatments. A new study explains why some forms of leukemia develop in very young children.

Also posted in Press releases | Tagged | Comments closed

Some Persistent Organic Pollutants Could Increase Breast Cancer Aggressiveness

Photo d'imagerie en microscopie électronique montrant la transformation des cellules mammaires tumorales dans le cancer du sein

Although persistent organic pollutants (POPs) are already suspected to promote breast cancer, there has been little research into how they affect its aggressiveness.

Also posted in Press releases, Public health | Tagged | Comments closed

Hormone therapy has a bigger impact than chemotherapy on women’s quality of life

Analysis of the CANTO cohort published in the journal Annals of Oncology will upset received wisdom on the effects that hormone therapy and chemotherapy have on the quality of life in women with breast cancer. Contrary to the commonly held view, 2 years after diagnosis, hormone therapy, a highly effective breast cancer treatment worsens quality of life to a greater extent and for a longer time, especially in menopausal patients. The deleterious effects of chemotherapy are more transient.

Also posted in Press releases | Tagged | Comments closed

Acting on the immune system even before cancer develops may be feasible

Researchers have shown that using immunotherapies at very early stages could potentially help prevent cancer.

Also posted in Press releases | Comments closed

Inserm Research Director Jérôme Galon Wins European Inventor Award 2019

Inserm researcher Jérôme Galon has been honored by the European Patent Office (EPO) for his Immunoscore®, a test that predicts relapse risk in patients with certain forms of cancer. An achievement that encapsulates the missions and results of Inserm, a research institute serving good health for all.

Also posted in Press releases | Tagged | Comments closed

Better air quality: what should the target values be for improving health?

To produce a significant reduction in mortality due to fine particulates, their average level should be reduced by at least 3 micrograms per m3 as a yearly average, concludes an interdisciplinary study.

Also posted in Press releases, Public health | Tagged | Comments closed

Human “Jumping Genes” Caught in the Act!

Over the course of evolution, the genomes of most living organisms have grown more complex thanks to transposable elements, a.k.a. “jumping genes,” or DNA fragments that can move and copy themselves from one chromosome location to another. Researchers from Inserm, the CNRS, Université Côte d’Azur, and Université de Montpellier were able to capture these “jumping genes” just after they moved.

Also posted in Molecular and structural bases of living organisms, Press releases | Tagged | Comments closed
RSS Youtube