Category Archives: Cancer

Ovarian cancer: A promising approach for treating the most aggressive forms using targeted therapy

Thanks to work done at Institute Curie by a team led by Fatima Mechta-Grigoriou, Inserm Research Director, it is now possible to identify, among women with aggressive ovarian cancer, those who could benefit from a promising targeted therapy.

A new type of sarcoma identified

Inserm teams led by Prof. Jean-Yves Blay and Christophe Caux in Lyon , and by Franck Tirode and Olivier Delattre in Paris have just demonstrated a new genetic variant in tumours that had not been identified until now

A new virus in liver cancer

More than a cause of a simple infection, viruses are often involved in the development of serious diseases. Such is the case with liver cancer, which often develops in an organ that has been weakened by hepatitis B or C virus. Researchers at Inserm have just identified the role of a new virus, hitherto unsuspected, in the occurrence of a rare type of liver cancer.

Production of iPS cells: discovery of the 5th element

Two teams of researchers from Inserm, CNRS, Centre Léon Bérard and Claude Bernard Lyon 1 University have discovered a molecule that may favour the production of these induced stem cells.

Restoring natural immunity against cancers

Scientists at the Institut Pasteur and Inserm have successfully increased the infiltration of immune cells into tumors, thus inducing the immune system to block tumor growth.

How a tumour mechanically transforms its healthy neighbouring cells into tumour cells and amplifies its own development

A growing tumour exerts considerable ongoing abnormal pressure on the healthy neighbouring cells. The CNRS/UPMC/Institut Curie team directed by Emmanuel Farge, Inserm Research Director at Institut Curie, has just discovered that this force can induce tumour gene expression.

Targeting a host receptor instead of the virus: a new experimental approach against hepatitis C virus.

Une collaboration internationale conduite par le Professeur Thomas Baumert met en évidence qu’un anticorps monoclonal spécifiquement dirigé contre la claudine-1, permet de prévenir et de traiter une infection chronique par ce virus dans un modèle animal.

Predicting the end of fertility for women after paediatric cancer

Researchers from the Paris Public Hospitals (AP-HP), Inserm, the Gustave Roussy and Curie Institutes, and Oscar Lambret Cancer Centre, coordinated by Dr Cécile Thomas-Teinturier of the Paediatric Endocrinology Service at Bicêtre Hospital, have studied the impact of certain therapeutic agents on the fertility of women who have been cured of a paediatric cancer.

Anne Dejean-Assémat, is awarded the Inserm Grand Prix for 2014

The Inserm Grand Prix is awarded to Anne Dejean-Assémat, director of Inserm/Institut Pasteur Joint Unit 993 “Nuclear Organization and Oncogenesis,” for her entire body of research on the molecular and cellular mechanisms involved in the development of human cancers.

Lung cancer diagnosed before it is detected by imaging

A team of researchers from Inserm led by Paul Hofman (Inserm Unit 1081/University of Nice) has just made a significant advance in the area of early diagnosis of invasive cancers.

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