
Blood stem cells have a surprising ability. In addition to ensuring the continuous renewal of blood cells, they keep track of past infections so that faster and more effective immune responses can be triggered in the future.
Blood stem cells have a surprising ability. In addition to ensuring the continuous renewal of blood cells, they keep track of past infections so that faster and more effective immune responses can be triggered in the future.
Driven by Inserm and the Directorate for Research, Studies, Assessment and Statistics (DREES) of France’s Ministry of Solidarity and Health, in conjunction with their partners (National Institute of Statistics and Economic Studies [INSEE], Public Health Agency, National Center for Scientific Research [CNRS], National Institute for Demographic Studies [INED], Université Paris-Saclay), EpiCOV is a large-scale epidemiological study based on a major statistical survey. It is proposing global and scientifically reliable mapping of population immune status and dynamics across the French territory through the collection of biological samples paired with questionnaires.
Inserm has played a leading role in the French and international research spheres, rallying its many experts in subjects related to fundamental research, therapeutic research, and modelling. Participating also in France’s solidarity effort, the Institute has taken action to distribute tens of thousands of masks, gloves, gowns, shoe covers and reagents to medical teams working in the nation’s hospitals.
For a deeper insight into the social and epidemiological challenges posed by the exceptional prevention measures taken in response to the COVID-19 pandemic – particularly confinement – a multidisciplinary group of researchers has joined forces with Inserm and the Public Health Agency to launch a survey of around 200,000 participants from five major French cohorts.
Un décret et un arrêté publiés le 5 avril autorisent les préfets à réquisitionner les laboratoires de recherche publique afin de procéder aux tests de dépistage du Covid-19 en utilisant la technique dite de RT-PCR, basée sur le matériel génétique. Le CNRS et l’Inserm se sont préparés en recensant, dans les laboratoires dont ils sont tutelles, le matériel disponible et le nombre de tests de ce type qui pourraient être réalisés par jour, dans les conditions fixées par le gouvernement. Une cinquantaine de structures, pouvant effectuer plus de 100 000 tests par jour, pourront être mises à contribution dès les prochains jours, sous la coordination de l’Inserm.
Cet essai clinique promu par l’AP-HP avec le soutien de l’Inserm et l’Établissement Français du Sang (EFS) consiste en la transfusion de plasma de patients guéris du Covid-19, contenant des anticorps dirigés contre le virus, et qui pourrait transférer cette immunité à un patient souffrant du Covid-19. Le plasma des personnes guéries du Covid-19 contient effectivement des anticorps développés par leur organisme et qui pourraient aider les patients en phase aiguë de la maladie à lutter contre le virus.
The teams of the Infectious and Tropical Diseases Hospital Bichat AP-HP and the University Hospital of Bordeaux, in collaboration with researchers from University of Paris, Inserm IAME UMRS-1137 (University of Paris / INSERM / University Sorbonne Paris Nord), the Institut Pasteur, the Hospices Civils de Lyon, CNRS – UMR 5308, Ecole Normale Supérieure de Lyon and University Claude Bernard Lyon, published a study based on the monitoring of the first five patients diagnosed Covid-19, admitted to Bichat hospital and the University hospital of Bordeaux.