Category Archives: Immunology, inflammation, infectiology and microbiology

Blood Stem Cell Immune Memory: A New Research Avenue in COVID-19

Blood stem cells have a surprising ability. In addition to ensuring the continuous renewal of blood cells, they keep track of past infections so that faster and more effective immune responses can be triggered in the future.

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EpiCOV: Population Immune Status Data to Guide Public Decision-Making

Driven by Inserm and the Directorate for Research, Studies, Assessment and Statistics (DREES) of France’s Ministry of Solidarity and Health, in conjunction with their partners (National Institute of Statistics and Economic Studies [INSEE], Public Health Agency, National Center for Scientific Research [CNRS], National Institute for Demographic Studies [INED], Université Paris-Saclay), EpiCOV is a large-scale epidemiological study based on a major statistical survey. It is proposing global and scientifically reliable mapping of population immune status and dynamics across the French territory through the collection of biological samples paired with questionnaires.

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Inserm’s commitment to the fight against the Covid-19 pandemic

Inserm has played a leading role in the French and international research spheres, rallying its many experts in subjects related to fundamental research, therapeutic research, and modelling. Participating also in France’s solidarity effort, the Institute has taken action to distribute tens of thousands of masks, gloves, gowns, shoe covers and reagents to medical teams working in the nation’s hospitals.

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COVID-19 and Confinement: A Large-Scale French Survey of Social Challenges and Health

For a deeper insight into the social and epidemiological challenges posed by the exceptional prevention measures taken in response to the COVID-19 pandemic – particularly confinement – a multidisciplinary group of researchers has joined forces with Inserm and the Public Health Agency to launch a survey of around 200,000 participants from five major French cohorts.

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Inserm and the African Countries: Partners in Fighting COVID-19

Image de microscopie du Coronavirus SARS-CoV-2 responsables de la maladie COVID-19 accrochés aux cellules épithéliales respiratoires humaines

Furthering scientific knowledge knows no frontiers. Therefore, Inserm would like to reaffirm that the countries of Africa are – more than ever – key scientific partners

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Covid-19 : le CNRS et l’Inserm mobilisés pour réaliser des tests de dépistage

Un décret et un arrêté publiés le 5 avril autorisent les préfets à réquisitionner les laboratoires de recherche publique afin de procéder aux tests de dépistage du Covid-19 en utilisant la technique dite de RT-PCR, basée sur le matériel génétique. Le CNRS et l’Inserm se sont préparés en recensant, dans les laboratoires dont ils sont tutelles, le matériel disponible et le nombre de tests de ce type qui pourraient être réalisés par jour, dans les conditions fixées par le gouvernement. Une cinquantaine de structures, pouvant effectuer plus de 100 000 tests par jour, pourront être mises à contribution dès les prochains jours, sous la coordination de l’Inserm.

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Coviplasm : tester l’efficacité de la transfusion de plasma de patients convalescents du Covid-19 dans le traitement de la maladie

Cet essai clinique promu  par l’AP-HP avec le soutien de l’Inserm et l’Établissement Français du Sang (EFS) consiste en la transfusion de plasma de patients guéris du Covid-19, contenant des anticorps dirigés contre le virus, et qui pourrait transférer cette immunité à un patient souffrant du Covid-19. Le plasma des personnes  guéries du Covid-19 contient  effectivement des anticorps développés par leur organisme et qui pourraient aider les patients en phase aiguë de la maladie à lutter contre le virus.

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Publication of a study in the journal The Lancet Infectious Diseases, covering the first five cases of Covid-19 identified in France and in Europe, between 24 and 29 January 2020

The teams of the Infectious and Tropical Diseases Hospital Bichat AP-HP and the University Hospital of Bordeaux, in collaboration with researchers from University of Paris, Inserm IAME UMRS-1137 (University of Paris / INSERM / University Sorbonne Paris Nord), the Institut Pasteur, the Hospices Civils de Lyon, CNRS – UMR 5308, Ecole Normale Supérieure de Lyon and University Claude Bernard Lyon, published a study based on the monitoring of the first five patients diagnosed Covid-19, admitted to Bichat hospital and the University hospital of Bordeaux.

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Deploying Cellphone Data to Fight COVID-19

Inserm has joined forces with telecommunications company Orange to study the impact of confinement on population mobility and explore how using aggregated cellphone data could improve COVID-19 pandemic predictions.

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Launch of a European clinical trial against COVID-19

A European clinical trial to evaluate four experimental treatments for COVID-19 starts this weekend. Coordinated by Inserm as part of the Reacting consortium, this trial will include at least 800 French patients with severe forms of COVID-19.

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