Category Archives: Neurosciences, cognitives sciences, neurology and psychiatry

Des résultats confirment la capacité du SARS-CoV-2 à infecter les neurones

Une étude internationale impliquant plusieurs équipes de l’Université de Yale (USA), de l’Institut du Cerveau (Sorbonne Université/Inserm/AP-HP/CNRS) et de l’hôpital Pitié-Salpêtrière AP-HP confirme la capacité du SARS-CoV-2 à infecter les neurones et en identifie plusieurs conséquences.

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Une thérapie génique innovante pour redonner la vue à des patients atteints d’une maladie rare

Les personnes atteintes de neuropathie optique héréditaire de Leber perdent la vue dès l’adolescence avec un déclin soudain au niveau des deux yeux, jusqu’à la cécité. Alors que les options de traitements étaient jusqu’ici très limitées, des chercheurs à l’Institut de la Vision ont conçu une approche de thérapie génique pour ces patients.

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Neuroscience Provides New Ways to Understand the Origin of Our Emotions

Are our emotions innate or are they the product of our culture and environment? This question has long been the subject of debate in the field of neuroscience. Researchers provide robust clinical data in favor of the second hypothesis. Their work suggests that our ability to know and recognize emotions is built up gradually and depends on our knowledge of language.

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A new cerebral canalopathy associating intellectual disability and abnormal movements

Dysfunctions of ion channels – or channelopathies – in the brain are today associated with more than 30 neurological diseases such as epilepsy or cerebellar ataxias. A study conducted at the Brain Institute (Sorbonne University / Inserm / AP-HP / CNRS) identified a new cerebral channelopathy originating from dominant mutations in the KCNN2 gene, encoding the SK2 ion channel.

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Découverte, chez la souris, d’un mécanisme pouvant expliquer l’anorexie et d’un traitement efficace transposable à l’homme

L’anorexie mentale est un trouble psychiatrique très sévère qui touche jusqu’à 4% de la population. De plus, c’est la maladie mentale avec le plus fort taux de mortalité (1% des personnes atteintes en meurent chaque année). À ce jour, il n’existe pas de traitement pharmacologique spécifique pour lutter contre cette maladie.

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Early Puberty: Is There a Potential Explanation for Some Cases?

A research team from Inserm, Lille teaching hospital and Université de Lille working at the Lille Neuroscience and Cognition Laboratory has discovered in mice a mechanism associated with the prepubertal growth spurt and the triggering of early puberty. This mechanism is regulated by the GnRH neurons, which orchestrate fertility, through the expression of their protein Nrp1.

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Research shows that treatment with growth hormone in children who have recovered from cancer does not increase the risk of a second tumor.

Les données d’une nouvelle étude confirment que le traitement par hormone de croissance suite à une radiothérapie chez les enfants qui présentent un déficit de cette hormone n’augmente pas le risque de survenue d’un second cancer.

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L’amnésie ne serait pas un marqueur systématique de maladie d’Alzheimer

Une étude montre que l’amnésie n’est pas spécifique de la maladie d’Alzheimer en se penchant sur le cerveau de patients décédés. Les résultats invitent à redéfinir la manière dont cette maladie est diagnostiquée aujourd’hui.

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Huntington’s Disease: Brain Abnormalities Detectable in Embryos

Huntington’s disease is a genetic neurological condition that usually manifests in adulthood. Teams of researchers and clinicians from Inserm, Université Grenoble Alpes, Sorbonne Université, CNRS and AP-HP at the Grenoble Institute of Neuroscience and the Brain Institute, have discovered abnormalities in the brains of human embryos that carry the mutation responsible for Huntington’s disease.

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Star-Shaped Brain Cells Shed Light on the Link Between Cannabis Use and Sociability

Cannabis use can lead to behavioral changes, including reduced social interactions in some individuals. To better understand the phenomenon, Inserm researcher Giovanni Marsicano and his team from NeuroCenter Magendie (Inserm/Université de Bordeaux), in collaboration with Juan Bolaños’ team from the University of Salamanca, have identified for the first time in mice the cerebral mechanisms underlying the relationship between cannabis and reduced sociability.

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