Category Archives: Neurosciences, cognitives sciences, neurology and psychiatry

La microscopie ultrasonore fonctionnelle : sonder l’activité du cerveau complet à l’échelle microscopique

Sorry, this entry is only available in French. Les ultrasons transforment le domaine de la neuroimagerie, grâce aux avancées technologiques réalisées au cours de la dernière décennie par le laboratoire Physique pour la Médecine (Inserm, ESPCI Paris – PSL, CNRS). L’introduction, en 2009, de l’imagerie fonctionnelle ultrasonore (fUS) a doté les neuroscientifiques d’une technologie unique […]

Pain Intensity Is Controlled by Our Internal Clock

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As with many of the body’s functions, pain intensity is controlled by our internal clock. This is what a team of Inserm researchers at the Lyon Neuroscience Research Center (Inserm/Université Claude Bernard Lyon 1/CNRS) has recently discovered. They show that pain oscillates over 24 hours with a peak at night and a decrease in the afternoon, regardless of the sleep-wake cycle or any external stimulation. This discovery could lead to new approaches to how we treat pain.

Questioning the Universal Application of Neurocognitive Tests

Crowd

A research team from Inserm, University Hospital Lille, and Université de Lille within the Lille Neuroscience & Cognition laboratory looked at the impact of cultural differences on the performances on two of the neurocognitive tests most used worldwide, comparing the results of around 600 healthy participants across 12 countries.

Inserm and CNRS to Lead Large-Scale Program on Psychiatry Research

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On July 18, 2022, France’s minister for Higher Education and Research Sylvie Retailleau announced an unprecedented psychiatry research effort in the form of 80 million euros allocated over five years to the precision-psychiatry project-program PROPSY, led by Inserm and CNRS as part of the Priority Research and Resources Programs (PEPRs).

Researchers described how the cerebellum modulates our ability to socialize

The cerebellum is essential for sensorimotor control but also contributes to higher cognitive functions including social behaviors. An international research consortium uncovered how dopamine in the cerebellum modulates social behaviors via its action on D2 receptors (D2R). These new findings pave the way to determine whether socially related psychiatric disorders, such as autism spectrum disorders (ASD), bipolar mood disorder, or schizophrenia, are also associated with altered dopamine receptors expression in specific cerebellar cell types.

Troubles du spectre de l’autisme : où en est la recherche ?

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Les trouble du spectre de l’autisme (TSA) résultent de particularités du neuro-développement. Ils apparaissent au cours de la petite enfance et persistent à l’âge adulte. Environ 700 000 personnes en France seraient concernées. Dans les laboratoires de recherche, les efforts se poursuivent, non seulement pour identifier de nouvelles options thérapeutiques mais aussi pour améliorer le repérage précoce des TSA et leur prise en charge psychosociale tout au long de la vie.

Le cervelet, une voie d’accès alternative pour traiter les mouvements involontaires provoqués par la maladie de Parkinson

Des chercheurs de l’Inserm, de l’ENS-PSL et du Collège de France, montrent que des stimulations depuis la surface du cerveau, au niveau du cervelet, suffisent à supprimer les mouvements involontaires ou dyskinésies liés à la maladie de Parkinson.

Do Some Cognitive Biases Contaminate Even Our Simplest Mental Mechanisms?

Enfants apprenant à écrire à l'école

In a new study analyzing data from all previous research in the field, researchers show that not only are positivity and confirmation biases present even in the simplest human and animal cognitive processes, but also that incorporating them into learning algorithms would enhance their performance.

Il existerait un lien entre la taille du réseau social et la structure du cerveau

Mère macaque toilettant son jeune singe.

With previous findings having highlighted the role of our social environment as one of the key factors behind the expansion of the cerebral cortex, researchers went one step further in elucidating this link. They were more specifically interested in a species of macaques whose brain architecture is comparable to that of humans. By observing these non-human primates in their natural state and by analyzing images of their brains, they discovered that the number of companions they have is predictive of the size of certain brain regions associated with social cognition and empathy.

Decoding a direct dialog between the gut microbiota and the brain

Schéma montrant le dialogue direct entre le microbiote intestinal et le cerveau

Scientists from the Institut Pasteur (a partner research organization of Université Paris Cité), Inserm and the CNRS have discovered that hypothalamic neurons in an animal model directly detect variations in bacterial activity and adapt appetite and body temperature accordingly. These findings demonstrate that a direct dialog occurs between the gut microbiota and the brain, a discovery that could lead to new therapeutic approaches for tackling metabolic disorders such as diabetes and obesity. The findings are due to be published in Science on 2022 04 15.

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