Category Archives: Neurosciences, cognitives sciences, neurology and psychiatry

Early Puberty: Is There a Potential Explanation for Some Cases?

A research team from Inserm, Lille teaching hospital and Université de Lille working at the Lille Neuroscience and Cognition Laboratory has discovered in mice a mechanism associated with the prepubertal growth spurt and the triggering of early puberty. This mechanism is regulated by the GnRH neurons, which orchestrate fertility, through the expression of their protein Nrp1.

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Le traitement par hormone de croissance chez les enfants guéris d’un cancer n’augmente pas le risque de survenue d’une seconde tumeur

Les données d’une nouvelle étude confirment que le traitement par hormone de croissance suite à une radiothérapie chez les enfants qui présentent un déficit de cette hormone n’augmente pas le risque de survenue d’un second cancer.

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L’amnésie ne serait pas un marqueur systématique de maladie d’Alzheimer

Une étude montre que l’amnésie n’est pas spécifique de la maladie d’Alzheimer en se penchant sur le cerveau de patients décédés. Les résultats invitent à redéfinir la manière dont cette maladie est diagnostiquée aujourd’hui.

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Huntington’s Disease: Brain Abnormalities Detectable in Embryos

Huntington’s disease is a genetic neurological condition that usually manifests in adulthood. Teams of researchers and clinicians from Inserm, Université Grenoble Alpes, Sorbonne Université, CNRS and AP-HP at the Grenoble Institute of Neuroscience and the Brain Institute, have discovered abnormalities in the brains of human embryos that carry the mutation responsible for Huntington’s disease.

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Star-Shaped Brain Cells Shed Light on the Link Between Cannabis Use and Sociability

Cannabis use can lead to behavioral changes, including reduced social interactions in some individuals. To better understand the phenomenon, Inserm researcher Giovanni Marsicano and his team from NeuroCenter Magendie (Inserm/Université de Bordeaux), in collaboration with Juan Bolaños’ team from the University of Salamanca, have identified for the first time in mice the cerebral mechanisms underlying the relationship between cannabis and reduced sociability.

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Publication of a multicentre observational study, in the journal JAMA Neurology, to identify risk factors for the severity of COVID-19 in patients with multiple sclerosis in France

A study, aimed at identifying the risk factors for the severity of COVID-19 in patients with multiple sclerosis in France, was carried out by teams from the neurology department of the Pitié-Salpêtrière hospital AP -HP, from the Brain Institute (Inserm / CNRS / Sorbonne University) at the Pitié-Salpêtrière hospital AP-HP, from Sorbonne University and the neurology service of the Strasbourg CHU.

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Un nouvel espoir dans la lutte contre la douleur causée par des lésions nerveuses

Des chercheurs du laboratoire Neuro-Dol (Université Clermont Auvergne et Inserm) viennent d’identifier deux pistes pharmacologiques qui pourraient ouvrir la voie à une nouvelle prise en charge de la douleur causée par des lésions nerveuses (douleur neuropathique). Une perspective encourageante quand 7 à 10% de la population est atteinte, sans réelle thérapeutique médicamenteuse efficace.

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Troubles de la conscience : deux nouvelles découvertes fondamentales pour le diagnostic et le traitement des patients

L’équipe de recherche PICNIC Lab dirigée par le Pr. Lionel Naccache à l’Institut du Cerveau (Sorbonne Université / Inserm / CNRS / AP-HP) publie deux études importantes concernant les malades souffrant d’un trouble durable de la conscience comme les patients en « état végétatif » ou en « état de conscience minimale ».

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L’imagerie ultrasonore pour résoudre le fonctionnement du cortex visuel

L’imagerie ultrasonore ultrarapide a récemment été proposée pour suivre l’activité cérébrale dans la profondeur du cerveau.

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Alzheimer’s Disease: Sweet Snacks May Not Go Down So Well in Those With a Genetic Predisposition

While genetic predisposition is a major factor in the risk of developing age-related dementia, and Alzheimer’s disease in particular, environmental factors such as diet also have an important role to play. Thanks to the 12-year follow-up of nearly 2,800 French people over the age of 65, a research team has sought to understand the impact of meals high in sugars (simple sugars and refined carbohydrates) on the risk of developing dementia. Its research shows a link between the consumption of sugars during the afternoon snack and the risk of developing Alzheimer’s disease in people with genetic predispositions.

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