Category Archives: Neurosciences, cognitives sciences, neurology and psychiatry

La thérapie génique, un espoir contre les maladies de Charcot-Marie-Tooth

Charcot Marie Tooth

Troubles de la marche et de l’équilibre, douleurs, atrophie musculaire… c’est le quotidien des 30 000 à 50 000 patients souffrant des maladies de Charcot-Marie-Tooth (CMT) en France. Des chercheurs de l’Inserm, de l’Université de Montpellier à l’Institut des Neurosciences de Montpellier (INM) et à l’Institut de médecine régénérative et de biothérapie (IRMB), en collaboration avec l’ISTEM à Evry, viennent d’obtenir des résultats prometteurs en ayant recours à un vecteur de thérapie génique

Weightlessness: A Challenge for Both the Body and the Brain!

Etude des mouvements

For the past 30 years, it was thought that the brain – responsible for motor control – worked to continuously compensate for the effects of gravity. In an initial study in 2016, the researchers had suggested that our brains use gravity to minimize the effort our muscles have to make. Those results were recently confirmed by new experiments conducted in collaboration with New York University on non-human primate models and humans.

The Vicious Circle of Anorexia Nervosa: Burning Calories May Well Be More Important Than Eating Less

Anorexie

In anorexia nervosa patients, the weight loss through lack of food is accompanied by fatigue and reduced physical capacity. Yet despite this they often continue to perform intense physical activity which contributes to that weight loss.

Huntington’s Disease: Exploring the Avenue of a Potential Neuroprotective Treatment

Huntington’s disease is a hereditary disorder that causes degeneration of the neurons involved in cognitive, motor and psychiatric functions. While existing treatments address the symptoms and relieve certain aspects of the disease, they cannot alter its course.

Charcot-Marie Tooth disease: A 100% French RNA-based therapeutic innovation

Charcot-Marie Tooth disease is the most common hereditary neurological disease in the world. It affects the peripheral nerves and causes progressive paralysis of the legs and hands. No treatment is currently available to fight this disease, which is due to the overexpression of a specific protein.

Communiquer pendant nos rêves, c’est possible !

Lorsque nous rêvons, nous sommes à première vue coupés du monde, incapables de recevoir des informations de l’environnement et d’y répondre. Pour la première fois, une collaboration entre des chercheurs de l’Inserm, de l’AP-HP, de Sorbonne Université et du CNRS avec plusieurs groupes américains, allemands et néerlandais, montre qu’une communication à double-sens, de l’expérimentateur vers le rêveur et vice-versa est possible au cours du rêve.

Better Access to Education Reduces Differences in Cognitive Capacity Between Men and Women

Elderly women are currently at a higher risk than men of developing dementia, particularly Alzheimer’s disease. A phenomenon that could partially be explained by inequalities in access to education between the sexes during the first half of the 20th century. Researchers from Inserm and Université de Paris, in collaboration with University College London, have shown that certain cognitive capacities have improved in women over recent generations, and that this is linked to a larger number of women accessing higher education.

Des résultats confirment la capacité du SARS-CoV-2 à infecter les neurones

Une étude internationale impliquant plusieurs équipes de l’Université de Yale (USA), de l’Institut du Cerveau (Sorbonne Université/Inserm/AP-HP/CNRS) et de l’hôpital Pitié-Salpêtrière AP-HP confirme la capacité du SARS-CoV-2 à infecter les neurones et en identifie plusieurs conséquences.

Une thérapie génique innovante pour redonner la vue à des patients atteints d’une maladie rare

Les personnes atteintes de neuropathie optique héréditaire de Leber perdent la vue dès l’adolescence avec un déclin soudain au niveau des deux yeux, jusqu’à la cécité. Alors que les options de traitements étaient jusqu’ici très limitées, des chercheurs à l’Institut de la Vision ont conçu une approche de thérapie génique pour ces patients.

Neuroscience Provides New Ways to Understand the Origin of Our Emotions

Are our emotions innate or are they the product of our culture and environment? This question has long been the subject of debate in the field of neuroscience. Researchers provide robust clinical data in favor of the second hypothesis. Their work suggests that our ability to know and recognize emotions is built up gradually and depends on our knowledge of language.

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