Category Archives: Circulation, metabolism, nutrition

Discovery of a Mechanism Explaining the Beneficial Action of Cancer Drug Tamoxifen on the Cardiovascular System

A commonly used treatment in some forms of breast cancer, tamoxifen acts on the cancer cells by blocking the estrogen receptor (ER)a and thereby inhibiting their proliferation. However, the action of this drug appears to be more complex than that, with the addition of protective effects on the arteries that could reduce the risk of developing cardiovascular disease.

Also posted in Press releases | Tagged | Comments closed

A Disruption of the Microbiota Is Linked to the Formation of a Molecule Promoting Type 2 Diabetes

An imbalanced diet has been linked to a disruption of the gut microbiota, which promotes metabolic diseases such as diabetes. Researchers have shown, in a large European cohort, that changes in the composition of the gut microbiota lead to increased blood levels of the molecule imidazole propionate. A molecule known to render the body’s cells resistant to insulin, thereby increasing the risk of developing type 2 diabetes.

Also posted in Press releases | Tagged | Comments closed

Links between nutrition and the brain: how a maternal omega-3 deficiency can influence the behavioural development of offspring in animals

Omega-3 fatty acids are essential, necessarily supplied by the diet and indispensable to brain development. Scientists have focused in particular on the impact of the maternal diet during gestation and lactation on the brain development of their offspring. They have thus shown for the first time in mice how an insufficient intake of omega-3 in the mother can alter the development of neuronal networks in the offspring, causing memory deficits. They have also deciphered the molecular mechanisms underpinning these effects.

Also posted in Press releases | Tagged | Comments closed

Rôle possible de l’exposition aux perturbateurs endocriniens dans la sévérité de la Covid-19

Une nouvelle étude révèle que l’exposition à des produits chimiques qui dérèglent le système endocrinien (les perturbateurs endocriniens ou PE) pourrait interférer avec différents signaux biologiques du corps humain jouant un rôle important dans la sévérité de la Covid-19.

Also posted in Press releases, Covid-19, Public health | Tagged | Comments closed

An Immune “Signature” to Identify Diabetic Patients at Risk of Developing Severe Covid-19

Type 2 diabetes is a risk factor for the development of a severe form of Covid-19. Identifying the immune- and inflammatory markers associated with these severe forms of the disease in this patient population would enable earlier and more appropriate care.

Also posted in Press releases, Covid-19 | Tagged | Comments closed

A New Therapeutic Target for Type 2 Diabetes Discovered Thanks to a Rare Disease

A new therapeutic target for type 2 diabetes has recently been identified by researchers from Inserm and Université de Strasbourg, in collaboration with several European hospitals.

Also posted in Press releases, Genetics, genomics and bioinformatics | Tagged | Comments closed

Les lymphocytes T non conventionnels chez les patients atteints de formes sévères de Covid-19 sont prédictifs de l’évolution de la maladie

Des chercheurs de l’Inserm, de l’Université de Tours et du CHRU de Tours ont découvert que les patients souffrant de formes sévères de Covid-19 présentent des changements dans une classe de cellules immunitaires connues sous le nom de « lymphocytes T non conventionnels ». L’étude suggère que surveiller l’activité de ces cellules dans le sang des patients pourrait permettre de prédire la gravité et l’évolution de la maladie.

Also posted in Press releases, Covid-19, Immunology, inflammation, infectiology and microbiology | Tagged | Comments closed

Comment la chirurgie bariatrique restaure la sécrétion d’insuline

Cellules β pancréatiques humaines produisant l’insuline (en rouge). L’ADN des cellules est marqué en bleu.

La chirurgie bariatrique est un traitement efficace de l’obésité sévère mais améliore également les co-morbidités associées dont le diabète de type 2 (DT2) par une restauration de la sécrétion d’insuline déficitaire.

Also posted in Press releases | Tagged | Comments closed

Microbiote : la géographie intestinale influence les interactions entre les bactéries et leurs virus

Les bactéries du microbiote sont soumises à la prédation de leurs virus, les bactériophages, mais une partie d’entre elles peut trouver refuge dans le mucus qui recouvre les tissus de l’intestin, permettant de garder les populations de bactériophages et de bactéries en équilibre.Telles sont les conclusions d’une étude dirigée par Laurent Debarbieux, directeur de recherche et responsable du laboratoire Bactériophage, bactérie, hôte à l’Institut Pasteur avec Luisa De Sordi, maître de conférences Sorbonne Université au Centre de recherche Saint Antoine (Sorbonne Université / Inserm).

Also posted in Press releases, Immunology, inflammation, infectiology and microbiology | Tagged | Comments closed

For diabetic patients confined during the Covid 19-epidemic, the AP-HP, in partnership with Inserm and University of Paris, launches CoviDIAB, a national application for information, prevention and support online

The AP-HP, the Federation of Diabetological Hospital Service and the AP-HP Connected Health Responsibility Centre offer this week to diabetic patients confined at home during the Covid-19 outbreak, a national programme of information, prevention and support for their health.

Also posted in Press releases, Public health | Tagged | Comments closed
fermer
fermer
RSS Youtube