Category Archives: Circulation, metabolism, nutrition

People with liver disease caused by eating too much sugar and fat could be at increased risk of developing serious neurological conditions like depression or dementia. In a study examining the link between non-alcoholic fatty liver disease (NAFLD) and brain dysfunction, scientists at the Roger Williams Institute of Hepatology, affiliated to King’s College London and the University of La²usanne, found an accumulation of fat in the liver causes a decrease in oxygen to the brain and inflammation to brain tissue – both of which have been proven to lead to the onset of severe brain diseases.

A new study reports clinical, biological, and imaging improvements in two infants with severe forms of disharmonious overgrowth syndromes treated with alpelisib. These are the first data obtained on the use of this molecule in severe neonatal forms of the disease.

La dysplasie fibromusculaire artérielle (DFM) est une anomalie de la paroi de certaines artères entraînant une augmentation du risque cardiovasculaire chez les personnes qui en sont atteintes. 3% de la population générale pourrait en être affectée et au moins 80% des personnes atteintes de cette maladie sont des femmes. Des chercheurs sont parvenus à décrire la composante génétique de la maladie, premier par vers l’identification de nouvelles cibles thérapeutiques.

Long considered an unnecessary organ, the appendix is now the focus of several studies that aim to better understand its role. Present in many mammals, including humans, it appears to have developed at least 16 times over the course of the evolutionary history of mammals, suggesting that its function must confer a positive selective advantage on those that have it.