Category Archives: Public health

Is physical activity always good for the heart?

Physical activity is thought to be our greatest ally in the fight against cardiovascular disease. But there may be significant variations in its protective effects across a range of different situations, such as regularly playing a sport, carrying heavy loads at work, or going for a walk with friends. These are the findings of a new study led by Inserm researcher Jean-Philippe Empana (U970 PARCC, Inserm/Université de Paris) in collaboration with Australian researchers.

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Study on the medico-economic implications of the level of insecurity in Inpatient Pediatrics

Teams of the Clinical Research Unit in Health Economics “ECO Île-de-France” * at the Hotel Dieu AP-HP, the Clinical Epidemiology Unit and Pediatric Endocrinology-diabetology Service hospital Robert Debré AP-HP, and mixed research unit INSERM / University of Paris U1123 “clinical Epidemiology and economic evaluation applied to vulnerable populations (ECEVE) conducted a study on the association between job insecurity, duration of hospital stay and hospital costs in pediatrics. More than four million pediatric visits were analyzed and insecurity was measured based on the standard of living of residence.

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Rare Diseases: Over 300 Million Patients Affected Worldwide

Rare diseases represent a global problem. Until now, the lack of data made it difficult to estimate their prevalence. Created and coordinated by Inserm, the Orphanet database, has made it possible to obtain a global estimate.

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Un « Google Maps » du système immunitaire pour prédire la réponse aux traitements contre le cancer

Une équipe conjointe Inserm et Institut Curie a développé une carte interactive des réponses immunitaires potentielles en cas de cancer.

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Skin graft: a new molecular target for activating stem cells

A joint study led by several teams open skin regeneration medecine to new insights.

Also posted in Cell biology, development and evolution, Press releases | Tagged | Comments closed

Some Persistent Organic Pollutants Could Increase Breast Cancer Aggressiveness

Photo d'imagerie en microscopie électronique montrant la transformation des cellules mammaires tumorales dans le cancer du sein

Although persistent organic pollutants (POPs) are already suspected to promote breast cancer, there has been little research into how they affect its aggressiveness.

Also posted in Cancer, Press releases | Tagged | Comments closed

Dysentery: Shigella, bacteria with adaptation to respiration

Imagerie montrant la déplétion de l'oxygène au sein de la muqueuse intestinale par Shigella (vert), induisant une hypoxie (rouge) au sein des foyers infectieux inflammatoires (neutrophiles: marqués à l'aide du Myelotracker, bleu).

Bacillary dysentery caused by the intestinal bacteria Shigella is a major health problem in tropical regions and developing countries. Complications from this infection lead to several hundred thousand deaths a year, primarily among infants. Researchers from Inserm and the Institut Pasteur have studied the mechanisms of Shigella virulence. They found that these bacteria are not only able to consume the oxygen in colonic tissue in order to grow and create foci of infection, but can also adapt their mode of respiration so that they can continue to grow once the oxygen in these foci has been used up.

Also posted in Immunology, inflammation, infectiology and microbiology | Tagged | Comments closed

Partially hydrolysed (hypoallergenic) baby formulas do not reduce allergy risks in infants

Hypoallergenic formulas are recommended for infants who are not exclusively breastfed and who are at risk of developing allergies. While it is assumed that such formulas reduce the development of allergies later in life, it is unclear whether this claim is true. A team of INRA and INSERM researchers have shown that the consumption of partially hydrolysed (hypoallergenic) formulas was not associated with a reduced risk of developing allergies, findings that were recently published in the journal Pediatric Allergy and Immunology.

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Consommation de boissons sucrées et risque de cancer

Des chercheurs rapportent une augmentation du risque de cancer chez les consommateurs de boissons sucrées dans la cohorte NutriNet-Santé.

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In France, 2 out of every 100 women are subjected to violence during their pregnancy

A joint team of researchers from Inserm and the University of Paris has investigated the frequency of physical abuse during pregnancy, its consequences for the mother and child, and the characteristics associated with this violence.

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