Monthly Archives: November 2013

Friday, 22th november 2013

Sorry, this article is only available in French.

Stanislas Dehaene is awarded the Inserm Grand Prix for 2013

Stanislas Dehaene, grand Prix Inserm 2013

The annual Inserm awards ceremony will take place on Monday 2 December at the Collège de France. On this occasion, eight prizes will be awarded to women and men who contribute daily to the scientific excellence of the Institute.
Stanislas Dehaene will be awarded the Inserm Grand Prix for his body of work on consciousness, Ogobara Doumbo will receive the International Prize for his research on malaria, and Daniel Louvard will be awarded the Honorary Prize for his work on cancer.

Chemotherapy: when our intestinal bacteria provide reinforcement

Research jointly conducted by investigators at Institut Gustave Roussy, Inserm, Institut Pasteur and INRA (French National Agronomic Research Institute) has led to a rather surprising discovery on the manner in which cancer chemotherapy treatments act more effectively with the help of the intestinal flora (also known as the intestinal microbiota).

Thrusday, 21th november 2013

Sorry, this article is only available in French.

Where and how are fear-related behaviours and anxiety disorders controlled?

A team of researchers at Inserm led by Cyril Herry (Inserm Unit 862, “Neurocentre Magendie,” Bordeaux) has just shown that interneurons located in the forebrain at the level of the prefrontal cortex are heavily involved in the control of fear responses. Using an approach combining in vivo recordings and optogenetic manipulations in mice, the researchers succeeded in showing that the inhibition of parvalbumin-expressing prefrontal interneurons triggers a chain reaction resulting in fear behaviour.

Comment détruire les stocks de VIH?

Éradiquer le VIH de l’organisme demeure inaccessible. En raison notamment de stocks de virus cachés dans des cellules du système immunitaire : les macrophages. L’équipe de Philippe Benaroch vient de montrer qu’il était possible, grâce à des anticorps, de bloquer la libération de ces ”troupes ennemies” des compartiments internes où elles sont regroupées. Cette découverte, publiée à la une de la revue Journal of Experimental Medicine, ouvre un nouveau front dans la bataille contre le virus du sida.

Wednesday, 20th november 2013

Sorry, this article is only available in French.

Tuesday, 19th november 2013

Sorry, this article is only available in French.

Cancer treatment: a step towards personalized chronotherapy

An international study conducted on mice and coordinated by researchers from Inserm, CNRS and Université Paris-Sud[1] has paved the way towards personalized chronotherapy treatments. In an article published in the journal Cancer Research, the team has shown that the timing of optimal tolerance to irinotecan, a widely used anti-cancer drug, varies by 8 hours depending on the sex and genetic background of mice. They then developed a mathematical model that makes it possible to predict, for each animal, the optimal timing for administering the drug.

Inserm and Fondation ARSEP organize the third meeting between researchers and patients

Multiple Sclerosis (MS) is a debilitating neurological disease which affects 80,000 individuals in France. At the moment, there is no known cause or cure. There are only treatments for the disease symptoms. Given the need to keep patients informed of progress in research, Inserm and Fondation ARSEP organise national meetings between researchers and patients every two years.

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