Monthly Archives: March 2017

Monday 20th March 2017

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Friday 17th March 2017

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Effects of the gut microbiota revisited

Matteo Serino, chargé de recherche Inserm à l’Institut de recherche en santé digestive (IRSD, une unité mixte de recherche Inserm/Université Toulouse III- Paul Sabatier/Ecole nationale vétérinaire de Toulouse/Inra), et ses collaborateurs, montrent que l’altération du microbiote intestinal, qu’elle soit d’origine nutritionnelle ou génétique, peut avoir des effets bénéfiques sur le métabolisme du foie. Ces résultats contredisent des résultats précédents obtenus dans le domaine qui montraient que le transfert d’un microbiote altéré avait forcément des conséquences négatives sur la santé. Ils viennent de paraître dans Molecular Systems Biology.

Posted in Press releases, Circulation, metabolism, nutrition | Tagged | Comments closed

Tuberculose et antibiorésistance : des chercheurs lillois inventent un nouveau prototype de médicament

Des chercheurs lillois (Inserm, Université de Lille, Institut Pasteur de Lille, CNRS)* ont inventé un prototype de médicament (SMARt-420**) capable de supprimer la résistance à l’éthionamide, un antibiotique utilisé pour traiter la tuberculose. Ces travaux sont publiés dans la revue Science*** datée du 17 mars 2017 et ouvrent une nouvelle voie dans la lutte contre la résistance aux antibiotiques.

Posted in Press releases, Immunology, inflammation, infectiology and microbiology | Tagged | Comments closed

Thursday 14th March 2017

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Discovery of an HIV reservoir marker: A new avenue toward eliminating the virus

French researchers have identified a marker that makes it possible to differentiate “dormant” HIV-infected cells from healthy cells. This discovery will make it possible to isolate and analyze reservoir cells which, by silently hosting the virus, are responsible for its persistence even among patients receiving antiviral treatment, whose viral load is undetectable. It offers new therapeutic strategies for targeting infected cells. This research is part of the ANRS strategic program “Réservoirs du VIH”. It is the result of a collaboration between the CNRS, Montpellier University, Inserm, the Institut Pasteur, the Henri-Mondor AP-HP hospital in Créteil, the Gui de Chauliac hospital (CHU de Montpellier) and the VRI (Vaccine Research Institute), and is published in the journal Nature on March 15, 2017. A patent owned by the CNRS has been filed for the diagnostic and therapeutic use of the identified marker.

Posted in Press releases, Genetics, genomics and bioinformatics | Tagged | Comments closed

Wednesday 15th March 2017

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Friday, March 17: World Sleep Day

Friday, March 17 will mark the 17th edition of World Sleep Day, an opportunity to raise general public awareness of the health impact of sleep.
Sleep is essential to brain maturation and development. It also plays a fundamental role in metabolic functions, notably by regulating the production of several hormones.

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Tuesday 14th March 2017

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Toward the synthesis of antibiotics by a new bacterial enzyme

Researchers at the French National Institute for Agricultural Research (Inra) and Inserm have discovered a new family of bacterial enzymes that can produce hitherto unidentified peptides with antibiotic activity. Published in Nature Chemistry, this work holds promise for the synthesis of molecules of pharmaceutical interest and the design of new antibiotics.

Posted in Press releases, Neurosciences, cognitives sciences, neurology and psychiatry | Tagged | Comments closed
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