Monthly Archives: May 2017

Friday 5th May 2017

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Thursday 4th May 2017

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Communication between neurons implicated in autism spectrum disorders and intellectual disabilities

An international collaborative study coordinated by Frédéric Laumonnier (Unit 930 “Imaging and Brain” Inserm/University of Tours) and Yann Hérault of the Institute of Genetics and Molecular and Cellular Biology (Inserm/ CNRS/ University of Strasbourg) provides new and original findings on the pathophysiological role of the contact areas between neurons in certain brain disorders. The study reveals that mutation of one of the genes involved in intellectual disability and autism spectrum disorder leads to dysfunction of the synapses, which are essential for neuronal communication.

Posted in Cell biology, development and evolution, Press releases, Genetics, genomics and bioinformatics, Neurosciences, cognitives sciences, neurology and psychiatry, Health technologies | Tagged | Comments closed

Wednesday 3rd May 2017

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Two blood tests for predicting the efficacy of a lung cancer treatment

ALK gene rearrangement is observed in 4% of non-small-cell lung cancer (NSCLC) patients. Researchers from Gustave Roussy, Inserm and Université Paris-Sud, have shown that two blood samples can now predict the efficacy of treatment (crizotinib). These blood samples (taken before treatment initiation and 2 months afterwards) are able to measure the changes in the number of circulating tumor cells[1] (CTC) with a specific genetic abnormality (abnormal number of ALK gene copies). A reduction in this cell count is predictive of longer relapse-free survival in these patients. This research was published in the Cancer Research journal on May 1st. It illustrates the potential of CTC as a liquid biopsy.

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Tuesday 2nd May 2017

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