Inserm Unit 1085 «Research Institute on helath, environment and work »
In a new study published in the journal Plos One, researchers from Inserm have analysed the causes of 79,107 deaths of Paris inhabitants aged over 35 years between 2004 and 2009. Their objective was to explore whether or not a combination of neighbourhood characteristics (socioeconomic profile and daily exposure to pollution) modified the risk of mortality during episodes of pollution such as those experienced in France during the heatwave of early summer 2015.
The choice of Paris as a city was not a random one, since the French capital is characterised by average pollution concentrations that vary enormously depending on the area, and by a variety of districts that are home to populations with diverse socioeconomic profiles.
Two maps of the Paris districts were constructed. In the first, one can see the distribution of populations according to socioeconomic status of the residential districts (units known as IRIS). The second depicts the mean annual concentrations of nitrogen dioxide (NO2) over the study period. In Paris, NO2 in the outdoor air is mainly associated with heating buildings and car traffic.
Dwellings housing the most disadvantaged people (category 3) are mainly located in the east and north of the city, whereas categories 1 and 2 are found in the centre and west part of Paris
The most polluted regions are seen close to the main major traffic routes, along the Périphérique (ring road) and the Seine, and in northwest Paris.
The results of the study show that short-term variations in pollution and mortality are generally linked, and that there is a genuine risk of excess deaths during peaks of pollution.
These results also show that subjects living in disadvantaged areas are more vulnerable to even brief episodes of atmospheric pollution. Most importantly, they indicate that this population, although chronically exposed to high levels of nitrogen dioxide (like other populations), is at a still higher risk during peaks of pollution.
To estimate the health of their elderly patients, healthcare professionals have various clinical tools at their disposal: geriatric assessment scales, health questionnaires and frailty scores. However, although these tests are appropriate to a medical context, they are more difficult for primary care ...
Between November 2014 and November 2015, a study conducted by Inserm (Unit 912 SESSTIM – Economic and Social Sciences, Health Systems and Medical Informatics), Université Aix-Marseille, IRD, CNRS and the PACA Regional Health Observatory, trialed the unit-dose dispensing of certain antibiotics across ...
Neighbourhood Characteristics and Long-Term Air Pollution Levels Modify the Association between the Short-Term Nitrogen Dioxide Concentrations and All-Cause Mortality in Paris
Séverine Deguen1,2*, Claire Petit1,2, Angélique Delbarre1, Wahida Kihal1,2,
Cindy Padilla1,2, Tarik Benmarhnia1,2, Annabelle Lapostolle3, Pierre Chauvin3,
1 EHESP School of Public Health, Rennes, France, 2 INSERM U1085 (IRSET), Rennes, France,
3 INSERM U707, Research Group on the Social Determinants of Health and Healthcare, Paris, France,
4 Lorraine University Medical School, Vandoeuvre-les-Nancy, France