Scientists from Inserm have just demonstrated how a high fat and sugar diet prevents the natural destruction of neurons from the enteric nervous system in mice.
The expression of p53 and Mdm2 is closely related. In an article published this week in the Cancel Cell review, Robin Fahraeus and his collaborators from Inserm Unit 940 (“Therapeutic Targets for Cancer”), demonstrate that cellular response to DNA damage requires involvement from the protein kinase ATM so that Mdm2 can positively or negatively control protein p53. […]
A study carried out by Eric Vivier and Sophie Ugolini at the Marseille-Luminy Centre for Immunology (Inserm/CNRS/Université Aix Marseille) has just reveal a gene in mice which, when mutated, can stimulate the immune system to help fight against tumours and viral infections. Whilst this gene was known to activate one of the body’s first lines […]
Romauld Lepers and Thomas Cattagni, researchers from Inserm Unit 1093 “Cognition, Action and Sensorimotor Plasticity” at the Université de Bourgogone, have analysed changes in participation and performance of runners aged 20 to 80 in the New York marathon over the last 30 years. The results are largely unexpected: the best male marathon runners over 65 […]
For the first time, a team from the Institute of Genetics and Molecular and Cellular Biology (IGBMC, Université de Strasbourg/CNRS/Inserm) has succeeded in taking a full, 3D photograph in HD (1) of a small vital,
Abundant evidence has clearly established an inverse association between age and cognitive performance, but the age at which cognitive decline begins is much debated.
On hearing the word ‘memory’, the brain normally springs to mind… or perhaps our immune system, which memorizes data to react more effectively should bacteria infect us a second time.
Inserm’s AVENIR “Genomic plasticity and aging” team, directed by Jean-Marc Lemaitre, Inserm researcher at the Functional Genomics Institute (Inserm/CNRS/Université de Montpellier 1 and 2), has recently succeeded in rejuvenating cells from elderly donors (aged over 100).
En étudiant chez l’animal l’action de deux antiépileptiques, l’équipe de Yehezkel Ben-Ari de l’unité Inserm 901 "INMED - Institut de neurobiologie de la méditerranée" vient de montrer comment les crises infantiles peuvent s’aggraver au fur et à mesure des répétitions et entraîner une perte d’efficacité des traitements classiques, notamment lorsqu’ils sont pris tardivement.
Des chercheurs de l’Institut de Génétique et de Biologie Moléculaire et cellulaire (CNRS / Inserm / Université de Strasbourg) sont parvenus à séquencer "image par image" l’initiation de la transcription de l’ADN, c’est-à-dire la copie de l’ADN en ARN. Le voile vient d’être levé sur une partie des mécanismes de cette étape cruciale. Les résultats de ces travaux, réalisés en collaboration avec une équipe de l’Université américaine Vanderbilt (Nashville,...
