A study conducted on mice by researchers at Inserm and UPMC (Pierre and Marie Curie University) offers a new type of immunotherapy approach for treating Alzheimer's disease. This involves amplifying a specific population of T lymphocytes that regulate immune and neuroinflammatory mechanisms that develop during the disease. These results are published in the journal Brain.
Faecalibacterium prausnitzii is an intestinal bacterium that is abundant in healthy adults but scarce in those suffering from inflammatory bowel disease. Using a mouse model, a team of scientists from INRA, INSERM, and the University of Auvergne has discovered that the bacterium possesses analgesic properties, a finding just published in Scientific Reports (January 18, 2016).Given that F. prausnitzii also exhibits anti-inflammatory effects, the bacterium shows great promise as a...
And if a simple oxygen mask were to protect people from neurological sequelae following an acute stroke? It would be sufficient to administer it to patients during the interval needed by medical teams to restore the blood supply, and hence oxygen, to the brain. At any rate, this is the hypothesis formulated by Jean-Claude Baron, Inserm Research Director at Unit 894, “Psychiatry and Neurosciences Research Center,” in collaboration with...
Researchers at Neurocentre Magendie (Inserm/University of Bordeaux) have just shown how altered connections between cells of the nervous system are involved in fragile X syndrome, a cause of severe autistic spectrum disorders. Using MRI, Andreas Frick, Inserm Research Fellow, and his team have actually observed, in a mouse model of this syndrome, an alteration in the connections and communication between different areas of the brain. These new data are...
The team led by Claire Wyart, an Inserm researcher at the Brain and Spine Institute, has just demonstrated the ability of sensory neurons located in the spinal cord to modulate movement. In the zebrafish, the researchers have shown that activation of these neurons triggers locomotion when the animal is at rest, and inhibits it when the animal is moving. These results offer hope that it will one day be...
Two Inserm research teams have just shown that failure of the intestine to produce a lipid “messenger” is associated with Crohn’s disease, a common and highly disabling inflammatory bowel disease (IBD).
The team led by Didier Leys and Régis Bordet (UMR-S 1171, Lille 2 University, Inserm, Lille University Hospital) has identified a biomarker that makes it possible to predict the risk of haemorrhagic complications from thrombolytic treatment following a Cerebrovascular Accident (CVA or stroke).
Researchers from Inserm and University of Bordeaux have just discovered that the cannabinoid receptors of the brain control these memories that are crucial for survival.
A team of French researchers has developed “an autobiographical memory”[1] for the robot Nao, which enables it to pass on knowledge learnt from humans to other, less knowledgable humans.
Scientists have just identified in the mouse, and then confirmed in humans, a new factor that regulates addiction. Glutamate, a neurotransmitter[1], contributes to regulating dopamine release in the nucleus accumbens, one of the cerebral structures of the reward system.