Researchers at INRA, INSERM, AP-HP, and UPMC have just discovered a new protein with anti-inflammatory properties, which has been named MAM (microbial anti-inflammatory molecule)
By increasing the stiffness of erythrocytes infected by the causal agent of malaria, Viagra favors their elimination from the blood circulation and may therefore reduce transmission of the parasite from humans to mosquitoes. This astonishing discovery, made by scientists from the CNRS, INSERM, Université Paris Descartes – at the Institut Cochin – and the Institut Pasteur, working in collaboration with a team from the London School of Hygiene and...
The INRA team, in collaboration with an American team (Berkeley), AgroParisTech, lnserm, AP-HP and UPMC, are answering these questions. Not only do their results show that F. prausnitzii plays an active role in protecting against intestinal inflammation, they also propose explanations regarding mechanisms of action.
Researchers demonstrated the efficacy of gene therapy treatment for Wiskott-Aldrich Syndrome (WAS). Six children that were treated and followed for at least 9 months had their immune system restored and clinical condition improved.
By analysing the genome of a little girl who contracted a severe form of influenza at the age of two and a half years, researchers have discovered that she has a genetic mutation, unknown until now, that causes a subtle dysfunction in her immune system.
Une collaboration internationale conduite par le Professeur Thomas Baumert met en évidence qu’un anticorps monoclonal spécifiquement dirigé contre la claudine-1, permet de prévenir et de traiter une infection chronique par ce virus dans un modèle animal.
Basic research on blood pressure has led researchers from Inserm (Inserm Unit 1138, “Cordeliers Research Centre”) to obtain unexpected results: drugs used to treat hypertension (high blood pressure) reduce side effects from corticosteroid-based creams used to treat certain skin diseases.
Preliminary data from the JIKI clinical trial, which is testing the efficacy of favipiravir in reducing mortality associated with Ebola, provide two important pieces of information: • absence of efficacy in individuals who arrive at treatment centres with a very high level of viral replication and who already have serious visceral involvement, • and encouraging signs of efficacy in individuals arriving at treatment centres with a high or moderate level of viral...
Scientists from the CNRS, INSERM and Université de Limoges have demonstrated that the production of type E immunoglobulins (IgE) by B lymphocytes induces a loss in their mobility and the initiation of cell death mechanisms.
A study has focused on the evolutionary history of the mycobacterium that causes tuberculosis, and more specifically on the Beijing lineage associated with the spread of multidrug resistant forms of the disease in Eurasia.