A clinical trial project, coordinated by Inserm, involving the testing of a preventive vaccine against Ebola has been selected by the European Commission.
The complete genomes of 16 anopheline mosquito species from the five continents have just been sequenced. Ten years of research have enabled an international consortium, coordinated by the University of Michigan and University of Notre Dame (United States) and including researchers from the French Institute for Development Research (IRD) and Inserm, to publish in the 27 November 2014 issue of the journal Science the DNA sequence for these mosquitoes,...
The Ebola epidemic is continuing to spread, particularly in West Africa. According to the latest report by the World Health Organisation (WHO) dated 17 October, 9,216 cases of Ebola have been recorded and 4,555 people have died of the virus. With the current situation of the Ebola epidemic, it quickly became necessary for French research to be mobilised rapidly.
Erosive oral lichen planus (OLP) is an auto-immune disease affecting skin and mucous membranes which results in an abnormal immune response against mucocutaneous cells.
By studying the mode of action of the interleukin-33 protein, an alarmin for white blood cells, a team at the Institut de Pharmacologie et de Biologie Structurale (IPBS - CNRS/Université Toulouse III - Paul Sabatier) has been able to evidence truncated forms of the protein that act as potent activators of the cells responsible for triggering allergic reactions.
La principale cause de mortalité chez les patients atteints de mucoviscidose est l’infection des poumons par différentes populations de bactéries qui varient en fonction de l’âge.
A novel mode of defense against bacteria such as the causal agent of tuberculosis or Staphylococcus aureus has been identified in humans by studying a small, aquatic flatworm, the planarian.
Having proven effective in reducing the number of new HIV infections in men, circumcision also appears to play a role in the reduction of HIV incidence in women. These findings are from the study ANRS 12126 coordinated by Professor Bertran Auvert (Inserm U1018, Université de Versailles-Saint Quentin, Hôpital Ambroise Paré) and conducted in the township of Orange Farm in South Africa. They will be presented as an oral communication...
The risk of transmission of HIV and of hepatitis C virus in intravenous drug users can be reduced significantly by means of support and educational sessions delivered by their peers. This type of community intervention, which is easily transposable, has been evaluated in the framework of ANRS AERLI, a study conducted jointly by the nonprofit organizations AIDES, Médecins du Monde and by Inserm U912 (Marseille). The results were presented...
Launched in March 2012, the ANRS 12249 TasP (Treatment as Prevention) Trial is one of four international randomized trials designed to assess the efficacy of the TasP strategy in a large population. It is conducted the province of KwaZulu-Natal, South Africa, one of the highest prevalence areas in the world, and the highest in South Africa (16.9% in 2012 according to the latest national survey of the general population).