In response to the 2014-2016 Ebola epidemic, the clinical development of a two-dose regimen of vaccines Ad26.ZEBOV and MVA-BN-Filo was accelerated. Approved in 2020 by the European Commission for use in epidemic emergencies, this regimen continues to demonstrate its relevance. An Inserm study has played a role in evaluating its safety and immunogenicity in healthy adults and in those with HIV and compared different time intervals between the two...
What if a few minutes of interaction with a chatbot could effectively address vaccine concerns? In an article published in the Journal of Experimental Psychology: Applied (28 October 2021), researchers from the CNRS, INSERM, and ENS-PSL show that such an interface is indeed capable of swaying the vaccine-hesitant.
A large number of researchers are currently mobilized to increase knowledge of SARS-CoV-2 in order to improve the treatment of infected patients and try to predict the future health impacts of infection with the virus. Researchers have been the first to identify a direct effect of SARS-CoV-2 on the brain’s blood vessels.
La dysplasie fibromusculaire artérielle (DFM) est une anomalie de la paroi de certaines artères entraînant une augmentation du risque cardiovasculaire chez les personnes qui en sont atteintes. 3% de la population générale pourrait en être affectée et au moins 80% des personnes atteintes de cette maladie sont des femmes. Des chercheurs sont parvenus à décrire la composante génétique de la maladie, premier par vers l’identification de nouvelles cibles thérapeutiques....
In 2013, a medical team proposed to the Haitian government and to Unicef a coordinated strategy to fight against cholera, aimed at breaking the chains of transmission. This strategy and its results, which show the apparent cessation of cholera transmission in Haiti since 2019, have just been the subject of a publication in the journal Emerging Infectious Diseases.
Teams of researchers published on October 4, 2021 in the journal Molecular Psychiatry (Nature Publishing Group) a summary of the results of the international literature on the central role that “ ceramides ”, a class of lipids, may play a role in SARS-CoV-2 infection.
Teams of researchers measured the antibody and cellular responses generated by a messenger RNA vaccine in patients with systemic lupus (LS). This work shows that vaccination is both well tolerated and effective, even against worrying variants. The factors associated with a poor vaccine response in some of these patients have been identified in order to better anticipate who should benefit from reinforced protective measures and / or adapted...
Afin de faciliter l’accès aux appels à projets et aux financements associés de la recherche, l’ADEME, l’ANR, l’Inserm dont l’ANRS | Maladies infectieuses émergentes, l’Anses et l’INCa regroupent l’ensemble de leurs appels à projets scientifiques sur un portail unique : appelsprojetsrecherche.fr.
The team of the adult nephrology-renal transplantation department of the Necker-Enfants Malades AP-HP hospital, Inserm and the University of Paris has carried out work, coordinated by Prof. Guillaume Canaud, which opens up new perspectives. therapies for patients with lymphatic abnormalities linked to a mutation in the PIK3CA gene.
How can lost neurons be regenerated? Using an animal model of epilepsy, the researchers have succeeded in transforming non-neuronal cells in the brain into new inhibitory neurons that reduce chronic epileptic activity by half. This research will in time make it possible to envisage a therapeutic application of this strategy.
