You just finished a good meal and are feeling full? Researchers from the CNRS, Inrae, University of Burgundy, Université de Paris, Inserm, and University of Luxembourg1 have just revealed the mechanisms in our brains that lead to this state. They involve a series of reactions triggered by a rise in blood glucose levels.
In animals, a vaccine modifying the composition and function of the gut microbiota provides protection against the onset of chronic inflammatory bowel diseases and certain metabolic disorders, such as diabetes and obesity.
Circulating tumor cells use the blood and lymphatic networks to disseminate within the body, forming metastases distant from the primary tumor. Inserm researcher Jacky Goetz and his Tumor Biomechanics team at the Molecular ImmunoRheumatology laboratory (Inserm/Université de Strasbourg) have helped to show that the flow properties of these biological fluids have a huge influence on the risk of developing metastases.
From the discovery of insulin in 1921 to the first ever pancreas transplants in the late 1960s, the recent history of type 1 diabetes research has brought scientific and medical advances which have transformed patient prognosis and quality of life. Here at Inserm, eleven teams distributed among nine units contribute their own endeavors. Their work primarily involves the characterization of pancreatic cells and improving knowledge of the disease (risk...
Atopic dermatitis, or eczema, primarily affects infants and children, and manifests itself in hypersensitivity to allergens in the environment. A skin disease characterized by flare-ups, it is often treated with topical anti-inflammatories. A new study shows that immune cells and sensory neurons interact in the skin to form units that can detect allergens and trigger inflammation. A discovery that provides an insight into how atopic dermatitis works, and points...
Des équipes de deux centres majeurs de transplantation rénale de l’AP-HP (à l’hôpital Necker-Enfants malades et à l’hôpital Saint-Louis) et de l’Université de Paris, ont coordonné, au sein du « Centre d’expertise de la transplantation d’organe » de l’unité Inserm 970 dirigé par le Pr Alexandre Loupy, une étude internationale ayant permis d’élaborer et de valider iBox, le premier algorithme universel de prédiction du risque de perte de rein...
Un consortium français vient de montrer que la consommation de certains lipides présents naturellement dans les produits laitiers (appelés « lipides polaires ») pourrait réduire le risque cardiovasculaire chez les femmes ménopausées et en surpoids.
A team of researchers are proposing a new radioactive tracer to locate atheromatous plaques in arterial walls, which can cause cardiovascular events.
Today, around 1 in 8 couples seek help because they are struggling to conceive. Infertility has therefore become a public health problem, and the scientific community is rallying in response.
A novel IT tool based on artificial intelligence methods has made it possible to identify the toxic effects of bisphenol S – a frequent substitute for bisphenol A in food containers.
Firibastat is the first in a new class of antihypertensive drugs targeting the renin-angiotensin system in the brain.
