Today, around 1 in 8 couples seek help because they are struggling to conceive. Infertility has therefore become a public health problem, and the scientific community is rallying in response.
A novel IT tool based on artificial intelligence methods has made it possible to identify the toxic effects of bisphenol S – a frequent substitute for bisphenol A in food containers.
Firibastat is the first in a new class of antihypertensive drugs targeting the renin-angiotensin system in the brain.
A team Sorbonne / AP-HP / Inserm, led by Professor Irene Netchine, physiology professor at Sorbonne University and pediatrician at the Hospital Armand Trousseau AP-HP, studied the molecular mechanisms of the clinical similarity between syndrome Temple and Russell Silver syndrome. Their study, published in Science Advances , highlights the importance of gene network concept "imprinted" in the diagnosis and treatment of patients with these rare syndromes.
A diet based on MON 810 or NK603 transgenic maize does not affect the health or metabolism of rats, under the conditions of the GMO 90+1 project1. This unprecedented study performed by a research consortium led by Inra brought together a number of partners2, including Inserm. The research was performed as part of the Risk’OGM program funded by the French Ministry of Ecological and Inclusive Transition. For six months,...
Restoring the action of insulin is one of the keys to fighting type 2 diabetes. Researchers from Inserm led by Dominique Langin at the Institute of Cardiovascular and Metabolic Diseases (Inserm/Université de Toulouse) are developing a therapeutic strategy that uses the properties of an enzyme (hormone-sensitive lipase) which, when stimulating fatty-acid synthesis in the fat cells, has a beneficial effect on insulin action. This research has been published in...
A group of over fifteen scientists, led by Samuel Vergès, an Inserm researcher from the “Hypoxia and Cardiovascular and Respiratory Physiopathologies” group (Inserm/Université Grenoble Alpes), is taking part in a scientific expedition to investigate the effect of low oxygen levels on health. In early 2019 they will spend 6 weeks in the world’s highest settlement, situated in Peru at an altitude of 5,300 m, studying how its inhabitants have...
Decreased jaw bone volume in edentate patients is the main difficulty which arises when fitting dental implants. Bone grafting is currently the most frequent solution for this problem. However, this method has several disadvantages, such as deterioration of the bone graft over time. Between 2010 and 2015, Pierre Layrolle, Inserm researcher, working with Norwegian and German teams as part of the REBORNE European project, tested an innovative technique for...
Inadequate protein intake in a gestating female is linked to lasting digestive abnormalities in her offspring. When studying the link between perinatal malnutrition and digestive system in rats, a team of researchers from Inserm in conjunction with Inra, Université de Nantes and University Hospital Nantes discovered functional digestive abnormalities in young rats and an inappropriate response to stress. Although conducted in animals, this research once again demonstrates the incidence...
Teams of rheumatology, respiratory medicine, genetics and the university hospital department FIRE Hospital Bichat Claude Bernard AP-HP, in collaboration with INSERM, Université Paris Diderot, the Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA, have discovered that a rare allele of rs35705950 variant gene MUC5B multiply by six the risk of occurrence of pulmonary fibrosis in patients with rheumatoid arthritis (RA). This broad study of genetic association...
