Excessive alcohol consumption is linked to a threefold increase in overall dementia risk and a twofold increase in that of developing Alzheimer’s disease, making it a major modifiable risk factor for these conditions. This is the conclusion of an Inserm study performed in collaboration with Canadian researchers via the QalyDays Study Group . Using exhaustive data on hospitalizations in France between 2008 and 2013, the researchers studied the link...
A team of researchers from Inserm ("Toxicology, pharmacology and cell signaling" JRU 1124) and the universities of Paris Descartes and Paris Diderot have recently discovered that flunarizine – a drug already used to treat migraine and epilepsy – enables the repair of a molecular defect related to spinal muscular atrophy, a severe and incurable disease. This discovery is the culmination of research efforts ongoing since 1995, when the Inserm...
February 28, 2018, marks the eleventh annual world Rare Disease Day, which carries the slogan “Show your rare. Show you care.” and the #ShowYourRare hashtag. World Rare Disease Day was created in 2008 by EURORDIS and the Council of National Alliances. Ninety countries will be participating in 2018. Orphanet: a Portal for Rare Diseases and […]
A team of researchers led by Maria-Christina Zennaro, Inserm research Director at the Paris Cardiovascular Research Center (Inserm/ Paris-Descartes University), in collaboration with German colleagues , has identified a new gene implicated in hypertension. This study has been published in Nature Genetics.These new findings highlight the role of genetic predisposition in the onset of common diseases and the importance of the French Plan for Genomic Medicine 2025. A...
A small revolution has taken place in the world of type 1 diabetes research. A study conducted by an Inserm team led by Roberto Mallone at the Cochin Institute (Inserm, CNRS, Paris Descartes University) is calling into question the role long attributed to the thymus in selecting and eliminating white blood cells associated with type 1 diabetes and reveals that we are all auto-immune. Discoveries which change our understanding...
A new study bringing together researchers from Inserm, Inra and University of Paris 13 (Center of Research in Epidemiology and Statistics Sorbonne Paris Cité, EREN team) suggests a link between the consumption of ultra-processed food and the additional risk of developing cancer. In total, 104,980 participants from the French NutriNet-Santé cohort were included. During the follow-up period (8 years), 2,228 cases of cancer were diagnosed and validated. ...
The rapidly-developing medical imaging field could well have found a novel technique in which multiple facets of a living being can be observed in real time and non-invasively. Teams from the Langevin Institute (ESPCI Paris - PSL University / CNRS), the biomedical ultrasound Technology Research Accelerator (Inserm A.R.T.) and the Paris-Cardiovascular Research Center (Inserm / Paris Descartes University) have developed a new medical imaging instrument which combines positron emission...
A team of Inserm researchers led by Howard Cooper (Inserm Unit 1208 "Stem Cell and Brain Institute") in collaboration with their colleagues in the U.S. have for the first time established a reference map of gene expression, by organ and time of day. A mammoth task that began a decade ago and has required two years of analysis. These results, published in Science, show just how important it is...
Could we have been wrong over the past 70 years in thinking that certain regions of the brain are insensitive to pain? This is what the findings of a team of researchers from Inserm, Nice University Hospital, Université Côte d’Azur and St Anne Hospital in Paris would suggest. By collecting observations of brief painful events occurring during brain surgery in awake patients, they found that certain structures – hitherto...
Prévus par la loi de bioéthique de 2011 et en amont de sa révision en 2018, les Etats généraux de la bioéthique se tiendront du 18 janvier au 7 juillet 2018. Ils ouvrent, à l’échelle nationale, un débat public organisé par le CCNE (Comité national d’éthique pour les sciences de la vie et de la santé).
