A study sponsored by the AP-HP has shown for the first time that asymptomatic individuals who carry the c9orf72 mutation, which means they are at risk of developing frontotemporal degeneration (FTD) or amyotrophic lateral sclerosis (ALS), experience cognitive, anatomical, and structural changes very early on, before age 40.The ability to identify these markers before disease symptoms appear is a major discovery, as such markers are crucial in developing therapeutic...
Since the COP 22, health has been a central topic of discussion. It is within this context, and on the day before the One planet Summit to be held tomorrow in Paris, that 10 principles for protecting respiratory health from climate change were proposed by an ad hoc workgroup from the Environment and Health Committee of the European Respiratory Society. Those principles have just been published in European Respiratory...
A team of researchers from ZIKAlliance discovers a specific mechanism of the infection
She replaces Thierry Damerval, who has been appointed Chairman and CEO of the French National Research Agency (ANR).
Thierry Damerval was appointed President and CEO of the French National Research Agency (ANR) by presidential decree on December 8, 2017, having been proposed for the role by the Minister for Higher Education, Research and Innovation.
Combining multiple vaccine administration routes achieves a better immune response. This is the finding of a recent study conducted as part of the European CUT’HIVAC project, coordinated by Béhazine Combadière, Inserm Research Director at the Center for Immunology and Infectious Diseases (CIMI-Paris, Inserm/Université Pierre et Marie Curie/ CNRS). This research opens new perspectives for "personalized" vaccination in which the immune system's response to infection can be adapted. This research,...
And what if meditation enhanced the aging process? This is suggested by the results of a pilot study, conducted by Inserm researchers based in Caen and Lyon. 73 individuals, with an average age of 65 years, underwent brain imaging tests. Among these individuals, "meditation experts" (with 15,000 to 30,000 hours of meditation to their name) showed significant differences in certain regions of the brain. By reducing stress, anxiety, negative emotions and sleep...
A revolution in the field of nanotechnology! An Inserm researcher in collaboration with Harvard University has succeeded in creating 3D shapes of unprecedented sophistication, thanks to the four DNA bases A, T, C and G. In practice, these researchers can create nanoscopic (10-9 m) objects from 30,000 DNA sequences that fold and self-assemble like LEGO® bricks. In time, this will make it possible to manufacture new tools adapted...
Our brains are constantly bombarded with sensory information. Far from being overloaded, the brain is an expert in managing this stream of information. Researchers from Neurospin (CEA/Inserm) have discovered how the brain incorporates and filters information.
Teams from Hôpital Paul-Brousse AP-HP, Inserm and Paris-Sud University have recently evidenced a mechanism which modulates the intestinal microbiota, involving a molecule with antioxidant and anti-inflammatory properties, known as REG3A. The latter is thought to protect the intestinal barrier and the bacteria most sensitive to oxygen forming the microbiota, thus improving "good" bacterial survival and growth. Transplantation of fecal microbiota in mice models of severe colitis or administration of...
