Teams from AP-HP, INRA, Gustave Roussy and Inserm can demonstrate the role of microbiota in the response of immunotherapy for cancer. They show that in man, the composition of gut microbiota can help to identify the patients who will respond favourably or not to treatment for melanoma, with Ipilimumab. This clinical study, carried out in 26 patients, suggests that a modification of the composition of gut microbiota could improve...
On the initiative of WHO, World Vaccination Week is the opportunity to raise public awareness of the vital importance of vaccination throughout life.The number of children in the world who are not vaccinated or are inadequately vaccinated is 19.4 million, according to WHO.In France, the latest data from the Institute of Health Monitoring (InVS) indicate that in children, there is vaccination coverage of 91% against diphtheria, tetanus, polio and...
A research team from Université Paris Descartes, Inserm and Centre Hospitalier Sainte‐Anne, led by Prof. Marie‐Odile Krebs, has shown that patients suffering from psychotic disorders, and exposed in utero to diethylstilbestrol, presented specific epigenetic changes. These changes correspond to genomic regions notably comprising gene ZFP57, known to play a role in neurodevelopment. Owing to this new project, the researchers examine the broader issue regarding the impact of in utero...
For children as well as adults, Easter is synonymous with chocolate. Known for its antioxydant qualities, among other things dark chocolate reduces the risk of diabetes and cell ageing. A good reason to make the most of it!
The European Patents Office (EPO) has just published its annual rankings: For the first time, Inserm has taken the top ranking for applicants in the pharmaceutical sector ahead of the big industrial companies and can confirm at the same time its top place as a European academic applicant in biomedical research.
The French National Institute of Health and Medical Research (Inserm), the US National Institutes of Health (NIH) and the London School of Hygiene & Tropical Medicine (LSHTM), in collaboration with health authorities in Guinea and Liberia, are launching a large clinical trial of candidate Ebola vaccines under the aegis of the PREVAC international consortium (Partnership for Research on Ebola VACcination).
A team of researchers in France, led by Dr. Ana Buj-Bello (Genethon/Inserm) and teams at the University of Washington and Harvard Medical School in the United States, achieved a new step towards the treatment of myotubular myopathy by gene therapy. The researchers demonstrated the efficacy of administration of a therapeutic vector by a single intravenous injection and identified the dose that restores long-term muscular strength in a large animal...
Le rôle des facteurs nutritionnels (alimentation et activité physique) dans le développement du surpoids et de l’obésité et dans la survenue de nombreuses maladies chroniques telles que les cancers, les maladies cardiovasculaires, le diabète et l’arthrose est à ce jour scientifiquement bien établi. Ces maladies constituent la première cause de mortalité à l’échelle de la planète et le nombre de patients concernés ne cesse d’augmenter.
In a study published on 1 April 2017 in the prestigious journal Cancer Discovery, research teams at Gustave Roussy, Inserm and Paris-Sud University demonstrate that analysing the molecular portrait of a malignant tumour makes it possible to identify the appropriate therapy and improve the prognosis of patients with cancer. MOSCATO, the biggest precision medicine study conducted to date, proves it for the first time.
Les individus apprennent à évaluer le niveau de prudence, de patience ou de fainéantise dont font preuve les autres après avoir observé leur comportement, mais surtout, cela influe sur leurs propres décisions, sans même qu’ils s’en rendent compte. Une découverte qui pourrait avoir des retombées en neurosciences. Les décisions de nos voisins inspirent-elles les nôtres ? C’est ce que laissent entendre les travaux de Jean Daunizeau et Marie Devaine,...
