Tag Archives: Press release

Identified: A Protein Essential for Chikungunya Virus Replication

Chikungunya is characterized by high fever and intense joint and muscle pain that can last for several months. The mechanisms of infection of human cells with the virus remain very poorly understood. Led by Ali Amara in collaboration with Marc Lecuit researchers from Inserm, Institut Pasteur, CNRS and Université de Paris have identified a protein that is crucial in order for the virus to replicate within its target cells.

Posted in Press releases, Immunology, inflammation, infectiology and microbiology | Tagged | Comments closed

Disarming a probiotic to improve its benefits

In a recent study, researchers managed to decipher certain pathways by which Escherichia coli Nissle 1917 produces both beneficial and toxic compounds. They then successfully created a modified strain with the same probiotic properties but an unactivated version of the toxin.

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A Single Dose of Yellow Fever Vaccine Does Not Offer Lasting Protection to all Children

The World Health Organization (WHO) recommends a single dose of the yellow fever vaccine for individuals aged 9 months or older living in or traveling to areas at risk of disease transmission, but there is a lack of data on its long-term efficacy when administered to infants. José Enrique Mejía, Inserm researcher at Unit 1043 Center for Pathophysiology of Toulouse Purpan and Cristina Domingo from the Robert Koch Institute in Berlin have recently shown that around half of children initially protected by the vaccination at 9 months of age lose that protection within the next 2 to 5 years, due to disappearance of the neutralizing antibodies.

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A novel, more effective method for diagnosing Alzheimer’s disease

According to a new study morphological analysis of the cortical sulci could make it possible to identify Alzheimer’s disease in 91% of cases.

Posted in Press releases, Neurosciences, cognitives sciences, neurology and psychiatry | Tagged | Comments closed

Elaboration et validation de l’iBox, le premier outil universel de prédiction du risque de perte de rein greffé basé sur l’intelligence artificielle.

Des équipes de deux centres majeurs de transplantation rénale de l’AP-HP (à l’hôpital Necker-Enfants malades et à l’hôpital Saint-Louis) et de l’Université de Paris, ont coordonné, au sein du « Centre d’expertise de la transplantation d’organe » de l’unité Inserm 970 dirigé par le Pr Alexandre Loupy, une étude internationale ayant permis d’élaborer et de valider iBox, le premier algorithme universel de prédiction du risque de perte de rein greffé.

Posted in Press releases, Circulation, metabolism, nutrition | Tagged | Comments closed

Du nouveau dans l’apprentissage automatique via des systèmes biologiques

Alors que les méthodes d’apprentissage automatique sont utilisées dans de nombreux domaines, y compris la santé humaine, leur application au monde du vivant est peu explorée à l’échelle moléculaire. Des chercheurs de l’Inra et de l’Inserm, viennent de réaliser un premier pas dans cette direction en créant un réseau neuronal simple dans un extrait cellulaire de bactérie Escherichia coli.

Posted in Molecular and structural bases of living organisms, Press releases | Tagged | Comments closed

Rôle des consultations génétiques dans le diagnostic des enfants et des adolescents atteints de troubles du spectre de l’autisme

Les recherches sur l’origine génétique des troubles du spectre de l’autisme (TSA) se sont significativement développées ces dernières années. Cependant, de nombreux patients concernés n’en bénéficient pas encore systématiquement. Une étude met en évidence l’intérêt d’étendre le dépistage génétique à un nombre plus important de patients souffrant de TSA avec déficit intellectuel.

Posted in Press releases, Genetics, genomics and bioinformatics | Tagged | Comments closed

Partially hydrolysed (hypoallergenic) baby formulas do not reduce allergy risks in infants

Hypoallergenic formulas are recommended for infants who are not exclusively breastfed and who are at risk of developing allergies. While it is assumed that such formulas reduce the development of allergies later in life, it is unclear whether this claim is true. A team of INRA and INSERM researchers have shown that the consumption of partially hydrolysed (hypoallergenic) formulas was not associated with a reduced risk of developing allergies, findings that were recently published in the journal Pediatric Allergy and Immunology.

Posted in Press releases, Public health | Tagged | Comments closed

New prebiotics: benefits without the downsides?

A research group led by Matteo Serino, Inserm researcher at the Digestive Health Research Institute (Inserm/Inra/ENVT/UT3 Paul Sabatier), has recently shown three plant extracts to have prebiotic effects in obese/diabetic mice, with a shorter duration of treatment and at lower doses to the prebiotics currently in use.

Posted in Press releases, Immunology, inflammation, infectiology and microbiology | Tagged | Comments closed

High-risk pregnancy: the interferon effect

Des chercheurs ont identifié un nouveau mécanisme cellulaire qui altère la formation du placenta et pourrait ainsi provoquer des complications graves pendant la grossesse. Il est lié à la production d’interféron, une molécule qui est produite en réponse à certaines infections, notamment virales.

Posted in Press releases, Immunology, inflammation, infectiology and microbiology | Tagged | Comments closed
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