Tag Archives: Press release

7ème rencontre nationale Recherche & Associations de malades

Plus de 120 représentants d’associations de malades et plus de 100 chercheurs et académiciens se retrouveront le 9 décembre prochain pour la 7ème édition des rencontres nationales “Recherche & Associations de malades”. Cet événement, organisé cette année en partenariat avec l’Académie des sciences et l’Académie nationale de médecine, aura pour thème “Partage des savoirs et perspectives de recherche”.

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Pancreatic Cancer: a “Multiomic” Study Identified Two Tumor Subtypes, and a Potential New Treatment Avenue

Juan Iovanna (Inserm Research Director) and his colleagues at the Marseille Cancer Research Center (Inserm/CNRS/Aix Marseille Université/Institut Paoli-Calmettes), in close collaboration with the “Tumor identity cards (CIT)” program run by the Ligue nationale contre le cancer and the University of Wisconsin (United States), have generated a “bank” of approximately 200 viable human pancreatic tumors, and cells derived from these tumors. The “multiomic” analysis of these tumors, i.e. the general characterization of all alterations in gene expression, epigenetic modifications of DNA methylation, has evidenced two main tumor subtypes. The specific characteristics of these subtypes, identified by the researchers, could open up new therapeutic approaches. The results of this research have been published in the journal Cell Reports.

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An Edible Mushroom With Potential to Fight Human Genetic Diseases

Could a common mushroom help fight certain genetic diseases? Although surprising, this is indeed the new discovery made by French scientists from Inserm, the French National Museum of Natural History, the CNRS, Université de Lille, and the Institut Pasteur de Lille[1]. By examining numerous extracts, the scientists thus evidenced that the mushroom, Lepista inversa, acted significantly on three isolated cell lines taken from patients with cystic fibrosis. This research was published in .Plos One

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Ribosome Plasticity: a New Avenue in Targeted Cancer Therapy

The “Nuclear Domains and Pathologies” team led by Jean-Jacques Diaz, Inserm Research Director at the Cancer Research Center of Lyon (Inserm/CNRS/Université Claude Bernard Lyon 1/Centre Léon Bérard), has recently demonstrated that one of the essential components of the “cellular machinery” that produces proteins – the ribosome – is altered in tumors. The researchers have observed that these modified ribosomes function differently in cancer cells, preferentially producing proteins that favor cancer cell proliferation and survival.  This discovery opens up new possibilities for the development of innovative cancer therapies that target this abnormal machinery. This research has been published in Proceedings of the National Academy of Sciences (PNAS).

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Edith Heard, Specialist in Epigenetics, Awarded the 2017 Inserm Grand Prize

On Thursday, November 30, at Collège de France, the annual Inserm Prize ceremony will honor nine researchers and engineers whose achievements have contributed to the institute’s scientific excellence. The 2017 Inserm Grand Prize will be awarded to Edith Heard for her work on epigenetics, in the presence of Frédérique Vidal, Minister of Higher Education, Research and Innovation; Cédric Villani, MP; Bruno Sido, Senator, President and First Vice-President of the Parliamentary Office for Scientific and Technological Assessment (Opecst).

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The consumption of antioxidant-rich foods is associated with a lower risk of type 2 diabetes

A lower risk of type 2 diabetes has been observed among individuals consuming food rich in antioxidants. This effect is largely contributed by fruit, vegetables, tea and other hot beverages, as well as moderate consumption of alcohol, as shown in a recent study from an Inserm research group, published in Diabetologia, the journal of the European Association for the Study of Diabetes (EASD)

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Efficacy of online nutritional coaching in patients with type 2 diabetes and abdominal obesity

A study coordinated by Dr. Boris Hansel and Prof. Ronan Roussel, from the Diabetes-Endocrinology and Nutrition Department at Hôpital Bichat – Claude-Bernard, AP-HP and the Cordeliers Research Center (Inserm/Pierre and Marie Curie University, Paris Diderot, Paris Descartes University) shows that online nutritional coaching -an automated nutritional support program- improves dietary habits and glycemic control in patients with type 2 diabetes and abdominal obesity.

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Probiotic Bacteria Produces Potent Analgesic

The intestinal microbiota still has surprises in store. The mode of action of a probiotic bacteria used in the symptomatic treatment of pain in irritable bowel syndrome has been revealed in a new study conducted by scientists from Inserm, Université de Toulouse and CHU de Toulouse [1] within the Digestive Health Research Institute (Inserm/INRA/Université Toulouse III – Paul Sabatier, ENVT). The bacteria produces a neurotransmitter (GABA) which, when bound to a lipid, crosses the intestinal barrier, acts on the sensory neurons located in the stomach, and reduces visceral pain. This new class of molecule, combining lipoprotein and GABA, could be used as a painkiller.

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Antibiotics affect the efficacy of immunotherapy

Une étude publiée dans la revue Science démontre que la prise d’antibiotiques affecte l’efficacité d’un traitement par immunothérapie chez des patients atteints d’un cancer.

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Interaction between brain and heart may be new indicator of state of consciousness

How do we know whether a patient is conscious when he or she is unable to communicate? According to an Inserm study conducted in 127 patients aged 17 to 80, changes in heartbeat in response to sound stimulation is a good indicator of state of consciousness. This is what Inserm researcher Jacobo Sitt and his team, based at the Brain & Spine Institute (ICM) at Pitié-Salpêtrière Hospital, AP-HP, demonstrate in an article published in Annals of neurology. This easy-to-perform examination complements the existing tests and enables finer predictive diagnosis, useful for both doctors and the patient’s loved ones.

Posted in Press releases, Neurosciences, cognitives sciences, neurology and psychiatry | Tagged | Comments closed
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