Tag Archives: Press release

BioPrint: Inserm Launches its Second Accelerator of Technological Research

La création d’Accélérateurs de Recherche Technologique est une priorité du plan d’orientation stratégique de l’Inserm. Ce 12 octobre 2017, l’Inserm inaugure son deuxième ART consacré à la “Bioimpression 3D” à Bordeaux. Il s’agit de la seule unité technologique utilisant les trois principales technologies de l’impression biologique en 3D, à savoir : le laser, le jet d’encre, et la micro-extrusion. Au sein de l’ART se côtoieront chercheurs et ingénieurs, afin de transformer le plus rapidement possible les avancées de la recherche en innovation technologique.

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First clinical proof of concept for functional ultrasound imaging of brain activity in newborns

Physicians from Inserm Unit 979 “Wave Physics for Medicine” at the ESPCI Paris together with clinician researchers from the neonatal intensive care unit of Robert-Debré AP-HP pediatric hospital and Inserm Unit 1141 have just made a scientific and medical breakthrough: the non-invasive imaging of brain activity in newborns using ultrasound. This will open up new avenues for bedside neurological diagnosis in full-term and premature babies. The details of their research have been published in the October 11, 2017 issue of Science Translational Medicine.

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Identification of a molecular mechanism associated with schizophrenia and bipolar disorder

A research team in psychiatry at CEA-Neurospin, together with the Mondor Institute of Biomedical Research (INSERM) and the Henri-Mondor (AP-HP) university hospitals, has shown that a genetic variant associated with several psychiatric conditions alters a prefrontal-limbic network, which may increase the risk of developing schizophrenia or bipolar disorder. The results of this study were published online on October 2, 2017 in Journal of Neuroscience.

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Maternal and neonatal health : preliminary results of the French National Perinatal Survey 2016

The French National Institute for Health and Medical Research (Inserm) and the Directorate of Research, Studies, Evaluation and Statistics (DREES) have published the preliminary results of the French National Perinatal Survey 2016. This report, based on a sample of births representing all births in France for the year 2016, presents the changes in the main perinatal indicators of health, medical practices and risk factors. It also describes the organization of healthcare in the country’s 517 maternity units.

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Biomedical Research Mobilized Around Thomas Pesquet

Space is an extraordinary laboratory for medicine and medical research on Earth. That is why Inserm and the CNES have been working together for more than a year[1] to accelerate research progress to improve the health of all of us. The presence of Thomas Pesquet, French astronaut from the European Space Agency (ESA), on board the International Space Station (ISS) for 6 months gave rise to many experiments, the preliminary results of which support the researchers’ hypotheses and sometimes even surprise them.

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Prenatal exposure to endocrine disruptors and behavioral problems in children

An epidemiological study carried out by Inserm on families from the EDEN cohort (500 boys born between 2003 and 2006 and their mothers) shows that exposure during pregnancy to certain phenols and phthalates is associated with behavioral problems in boys between 3 and 5 years of age. The most worrying compounds in this respect are bisphenol A, triclosan and dibutyl phthalate (DBP).

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How do arteries protect themselves from atherosclerosis?

Associated with an aging population and the development of metabolic syndrome, atherosclerosis is a leading cause of death worldwide. Researchers from Inserm Unit 970, the “Paris Cardiovascular Research Center” (Inserm/Université Paris Descartes), have succeeded in revealing the mechanisms underlying the formation of atherosclerotic plaques. In particular, they have discovered the protective role of autophagy, a mechanism for cleaning and recycling cell components, in the cells that line the inner artery wall. These results, published in PNAS on September 25, 2017, provide us with an improved understanding of the initial stages of plaque development, and open up the possibility of developing a preventive treatment.

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The Yin and Yang of Low-dose Irradiation on Hematopoiesis

A team of researchers from CEA, Inserm, and the Paris-Sud and Paris Diderot universities has shown that exposure to low doses of irradiation (0.02 Gy) leads of a loss of hematopoietic stem cell[1] (HSC) function. The team has also shown that irradiation at this low dose facilitates efficient bone marrow transplantation without myeloablation[2]. These results, published in Cell Reports on September 26, 2017, show both the positive and negative aspects of low doses of irradiation.

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Maternal mortality: deaths from hemorrhage reduced but inequalities remain

Between 2010 and 2012, 256 women died in France from causes linked to pregnancy, labor, or following childbirth, amounting to 85 such cases a year. Although inequalities remain, improvements have been observed in the provision of labor care, with the death rate from hemorrhage halving. These epidemiological results have been made public by the triennial report of the Confidential Inquiry into Maternal Deaths (Enquête Confidentielle sur les Morts Maternelles, ENCMM) in regard to the period 2010-2012, which was led by Inserm’s EPOPé – “Obstetrical, Perinatal, and Pediatric Epidemiology Team” – at the Center of Research in Epidemiology and Statistics Sorbonne Paris Cité (CRESS, Unit 1153).

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“Humanized” Mouse Model Developed to Study Hepatitis B Infection

The ANRS consortium “Humanized Mouse Models for Viral Hepatitis”1, made up of 6 teams of researchers, has developed a mouse model for studying the interaction between the immune system and the liver following infection by the hepatitis B virus. This research, coordinated by Dr. Hélène Strick-Marchand (Inserm joint unit 1223, “Physiopathology of the Immune System”, Institut Pasteur), responds to a real lack of animal models for studying this disease and thus opens up the possibilities for evaluating new therapeutic strategies. These results have been published in the journal Gastroenterology.

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