Tag Archives: Press release

Hypertension: A New Drug Coming Soon?

Firibastat is the first in a new class of antihypertensive drugs targeting the renin-angiotensin system in the brain.

Posted in Press releases, Neurosciences, cognitives sciences, neurology and psychiatry, Circulation, metabolism, nutrition | Tagged | Comments closed

ChroMS – the brain as never seen before

ChroMS is a new microscopy technique bringing together color, 3D and high-resolution imaging, and is nothing short of a revolution in vertebrate brain imaging.

Posted in Press releases, Neurosciences, cognitives sciences, neurology and psychiatry | Tagged | Comments closed

Flu Shot: Cutaneous Administration Improves Efficacy

The team of Béhazine Combadière, Inserm Research Director at Unit 1135 “Center for Immunology and Infectious Diseases”, has been working for years on the impact of vaccine administration routes on the quality of immune responses.

Posted in Press releases, Immunology, inflammation, infectiology and microbiology | Tagged | Comments closed

(Français) Effets du lithium sur le cerveau dans le traitement du trouble bipolaire : vers la confirmation d’un mécanisme d’action

(Français) Un nouvel éclairage est apporté sur l’action du lithium dans le traitement des troubles bipolaires.

Posted in Press releases, Neurosciences, cognitives sciences, neurology and psychiatry | Tagged | Comments closed

Cesarean Delivery Linked to Increased Risk of Severe Maternal Complications

Cesarean delivery is thought to be linked to a greater risk of severe maternal complications – primarily hemorrhagic – than vaginal delivery, especially in women aged 35 and over.

Posted in Press releases, Public health | Tagged | Comments closed

Narcolepsy: A New Drug to Fight Sleepiness

How can the quality of life of patients with narcolepsy, the severest sleep disorder in humans, be improved? An international scientific team led by Yves Dauvilliers, a researcher at Inserm and Université de Montpellier, is working on Solriamfetol – a promising new drug that stimulates alertness and improves resistance to sleepiness.

Posted in Press releases, Neurosciences, cognitives sciences, neurology and psychiatry | Tagged | Comments closed

La première cartographie complète de la latéralisation des fonctions cérébrales

(Français) Certains processus cérébraux sont réalisés préférentiellement dans l’hémisphère droit ou l’hémisphère gauche du cerveau. Mais quelles fonctions et quel hémisphère ? Une équipe de recherche franco-italienne dirigée par un chercheur CNRS de l’Institut du cerveau et de la moelle épinière (AP-HP/CNRS/Inserm/Sorbonne Université) vient de répondre à cette question en livrant la première cartographie complète de la latéralisation des fonctions cérébrales, publiée le 29 mars 2019 dans la revue Nature Communications. Leurs résultats montrent pour la toute première fois que la prise de décision, comme la perception et l’action ainsi que les émotions, fait plus appel à l’hémisphère droit. Au contraire de la communication symbolique, qui repose plus sur l’hémisphère gauche.

Posted in Press releases, Neurosciences, cognitives sciences, neurology and psychiatry | Tagged | Comments closed

Nanoblades: shuttles for genome surgery

Researchers are now able to edit the genome with precision using the “gene editing scissors” of CRISPR-Cas9, which is a highly promising tool for gene therapy. The technical challenge now is to get this tool into the genome of certain cells. With this in mind, a joint team from Inserm, the CNRS, the Université Claude Bernard Lyon 1, and the École Normale Supérieure de Lyon, working within the International Center for Infectiology Research (CIRI), have developed capsules that allow CRISPR-Cas9 to reach the target DNA: Nanoblades.

Posted in Cell biology, development and evolution, Press releases, Immunology, inflammation, infectiology and microbiology | Tagged | Comments closed

HIV/tuberculosis co-infection: tunnelling towards better diagnosis

1.2 million people in the world are co-infected by Mycobacterium tuberculosis, the bacteria which causes tuberculosis, and AIDS (HIV-1). This combination is deadly: it makes patient diagnosis and treatment difficult, and increases the pathogenicity of these two infectious agents. An international team led by researchers at the CNRS and Inserm have revealed that in the presence of tuberculosis, HIV-1 moves from one cell to the next via nanotubes which form between macrophages, drastically increasing the percentage of infected cells. These findings appear in the 26 March 2019 edition of Cell Reports.

Posted in Press releases, Immunology, inflammation, infectiology and microbiology | Tagged | Comments closed

A Gene Therapy Tested in the Treatment of Myotubular Myopathy

Inserm and CNRS researchers from the Institute of Genetics and Molecular and Cellular Biology (Inserm/CNRS/Université de Strasbourg) have discovered how myotubularin – a protein deficient in myotubular myopathy – interacts with amphiphysin 2 and suggest targeting the latter in order to treat patients.

Posted in Cell biology, development and evolution, Press releases, Genetics, genomics and bioinformatics | Tagged | Comments closed
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