Tag Archives: Video press release

Alzheimer’s disease: simplified diagnosis, with more reliable criteria

How many patients receive an incorrect diagnosis of Alzheimer’s disease? The answer is a surprisingly high number: over a third! To reduce the number of errors, the diagnostic criteria must be the most reliable possible, especially at the very early stages of the disease. For the last decade, an international team of neurologists, coordinated by Bruno Dubois (Inserm/Pierre and Marie Curie University/AP-HP Joint Research Unit 975) has been working towards this. In the June issue of The Lancet Neurology journal, we see how the researchers have developed a simplified diagnosis based on the most specific criteria of the disease. A challenge primarily for research, but also for clinical practice.

Why does the brain remember dreams?

sommeil

Some people remember their dreams every morning, whereas others rarely remember them. A team led by Perrine Ruby, an Inserm Researcher has studied the brain activity of these types of dreamers in order to understand the differences between them.

A good outcome for the CHILD-INNOVAC project: successful test in humans of a nasal vaccine against pertussis

The CHILD-INNOVAC European research programme, coordinated by Inserm, has enabled the development of an innovative vaccine that can be administered intranasally, to combat pertussis, which has shown a resurgence in developed countries in recent years. The research consortium, headed by Camille Locht, Director of the Centre for Infection and Immunity of Lille (a joint Unit involving Inserm, CNRS, Institut Pasteur de Lille and University of Lille Nord de France), today published promising results from Phase I clinical trials of the vaccine in human subjects in the online journal PLOS ONE.

Molecule discovered that protects the brain from cannabis intoxication

Two INSERM research teams led by Pier Vincenzo Piazza and Giovanni Marsicano (INSERM Unit 862 “Neurocentre Magendie” in Bordeaux) recently discovered that pregnenolone, a molecule produced by the brain, acts as a natural defence mechanism against the harmful effects of cannabis in animals.

An analgesic molecule discovered in its natural state in Africa

plant de citronnier

A team of researchers led by Michel De Waard, Inserm Research Director at the Grenoble Institute of Neurosciences (Inserm, University Joseph Fourier, CNRS), has discovered that an African medicinal plant produces large quantities of molecules with analgesic properties.

Early exposure to bisphenol A might damage the enamel of teeth.

Are teeth the latest victims of bisphenol A? Yes, according to the conclusions of work carried out by the research team led by Ariane Berdal of the Université Paris-Diderot and Sylvie Babajko. The researchers have shown that the teeth of rats treated with low daily doses of BPA could be damaged by this. Analysis of the damage shows numerous characteristics that are common with a recently identified pathology of tooth enamel that affects roughly 18% of children between the ages of 6 and 8.

Optogenetics is proving to be highly promising in the treatment of obsessive-compulsive disorders

Thanks to work carried out by the Massachusetts Institute of Technology in Boston, Eric Burguière, an Inserm researcher working in the MHI research centre and his co-workers have succeeded in reducing the compulsive behaviour of mice using optogenetics, a technique that combines light stimulation with genetic engineering.

‘Diet’ drinks associated with increased risk of Type II diabetes

Françoise Clavel-Chapelon, (Director of Research at INSERM-University of Paris-Sud 11, at the Institut Gustave Roussy), and Guy Fagherazzi were interested in a connection between the consumption of ‘diet’ or ‘light’ soft drinks and the risk of Type II diabetes. The analysis performed on 66,188 women in the E3N cohort confirms a link between sweet soft drinks and type II diabetes and reveals for the first time in France that, contrary to received wisdom, there is a higher risk of diabetes from so-called ‘diet’ or ‘light’ drinks than from ‘normal’ sweetened soft drinks.

New bacteria to fight against intestinal inflammation

Élafine (en vert) libérée par la bactérie recombinante à la surface du colon d'une souris traitée. En rouge, les cellules épithéliales. En bleu, les noyaux cellulaires.

Nathalie Vergnolle, director of research at Inserm, and her team at the Centre for Physiopathology at Toulouse Purpan (CPTP Inserm / Université Toulouse III – Paul Sabatier /CNRS), with Philippe Langella director of research at INRA and his team at the Institut Micalis[1], in collaboration with the Institut Pasteur, have recently succeeded in producing “beneficial bacteria” capable of protecting the body against intestinal inflammation.

A white mouse …

souris blanches et noires

Mice with black fur that turns white? Specialist cancer researchers have taken steps to better understand the development of skin cells responsible for pigmentation

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