Effects of an 18-month meditation training on regional brain volume and perfusion in older adults: The Age-Well randomized, single-blind, controlled trial of the Medit-Ageing European project
Gael Chételat,* PhD1; Antoine Lutz,* PhD2; Olga Klimecki,† PhD3; Eric Frison,† MD4; Julien Asselineau, MSc4; Marco Schlosser, MSc5,6; Eider M. Arenaza-Urquijo, PhD1,7; Florence Mézenge, MSc1; Elizabeth Kuhn, PhD1; Inès Moulinet, PhD1; Edelweiss Touron, MSc1; Sophie Dautricourt, PhD1; Claire André, PhD1; Cassandre Palix, MSc1; Valentin Ourry, PhD1; Francesca Felisatti, MSc1; Julie Gonneaud, PhD1; Brigitte Landeau, MSc1; Géraldine Rauchs, PhD1; Anne Chocat, MD1; Anne Quillard, MD1; Eglantine Ferrand Devouge, MD1,8,9; Patrik Vuilleumier, MD3; Vincent de La Sayette, MD10; Denis Vivien, PhD1; Fabienne Collette,‡ PhD11; Géraldine Poisnel,‡ PhD1; Natalie L. Marchant,‡ PhD5; for the Medit-Ageing Research Group.
1 Normandie Univ, UNICAEN, Inserm, U1237, PhIND « Physiopathology and Imaging of Neurological Disorders », Institut Blood and Brain @ Caen-Normandie, Cyceron, 14000 Caen, France.
2 Lyon Neuroscience Research Center Inserm U1028, CNRS UMR5292, Lyon 1 University, Lyon, France.
3 Swiss Center for Affective Sciences, Department of Medicine, University of Geneva, Geneva, Switzerland.
4 EUCLID/F-CRIN Clinical Trials Platform, Inserm, CHU Bordeaux, Univ. Bordeaux, CIC1401-EC, Bordeaux, France.
5 Division of Psychiatry, University College London, London, United Kingdom.
6 Department of Psychology, Faculty of Psychology and Educational Sciences, University of Geneva, Geneva, Switzerland.
7 Barcelonabeta Brain Research Center, Fundación Pasqual Maragall, Barcelona, Spain.
8 Normandie Univ, UNIROUEN, Department of General Practice, Rouen, France.
9 Rouen University Hospital, CIC-CRB 1404, F 76000, Rouen, France.
10 CHU Caen-Normandie, Department of Clinical Research, Caen, 14000, France.
11 GIGA-CRC, In Vivo Imaging, Université de Liège, Liège, Belgium and Belgian National Fund for Scientific Research.
*Co-first authors
†Co-second authors
‡Co-last authors
JAMA Neurology : https://doi.org/10.1001/jamaneurol.2022.3185