The zebrafish is particularly studied in research laboratories due to its ability to regenerate its caudal fin. This study opens up new avenues for improving our understanding of the regeneration processes, with the aim of developing clinical applications in the field of regenerative medicine.
The use of animals for scientific purposes is based on the principles of the 3Rs (Replacement, Reduction and Refinement) to provide the best guidance to research and promote responsible and innovative methods. A group of research players comprising Inserm, CNRS, INRAE, Inria, CEA, Institut Pasteur de Paris, CPU, and the association Udice has announced the creation in France of FC3R (France Center 3R) to support the application of the...
Researchers from Inserm, Lille University Hospital and Université de Lille, at the Lille Neuroscience and Cognition laboratory, have discovered one of the mechanisms by which endocrine disruptors can alter reproductive function development from birth.
Le diagnostic de maltraitance physique chez le nourrisson peut être difficile à établir. Pour guider les professionnels de santé, des recommandations définissant les pratiques à adopter lors d’une suspicion de maltraitance physique sont produites par des sociétés savantes, des autorités publiques ou par des groupes d’experts indépendants. Malgré ce cadre, les prises en charge observées sont différentes en fonction des praticiens, en France comme dans d’autres pays avec des...
Le 19 octobre, les représentants de dix établissements, dont l'Inserm, membres du Groupement d’intérêt scientifique (GIS) de l’Observatoire épidémiologique dans les eaux usées (Obépine), se sont réunis pour la première fois.
While the care and treatment of acute myeloid leukemia (AML) have greatly improved in recent years, overall survival remains low. Resistance to the various treatments continues to present a major clinical challenge. Using animal models, and also by working with patients themselves, scientists have identified a new biomarker predictive of response to dual therapy (chemotherapy plus targeted therapy) used in AML, as well as resistance mechanisms behind relapses.
Our ability to understand the syntax of complex sentences is one of the most difficult language skills to acquire. In 2019, research had revealed a correlation between being particularly proficient in tool use and having good syntactic ability. A new study has now shown that both skills rely on the same neurological resources, which are located in the same brain region. Furthermore, motor training using a tool improves our...
La pandémie de Covid-19 s’est accompagnée d’une dégradation de l’état de santé mentale d’une grande partie de la population française. Des chercheurs montrent que les étudiants sont particulièrement vulnérables. Pendant les deux premiers confinements, les prévalences des troubles anxieux et dépressifs, ainsi que des pensées suicidaires, étaient plus élevées dans cette population en comparaison à des non étudiants. Ces résultats, mettent en lumière la nécessité d’une grande vigilance en...
Researchers carried out work, to study the genetic cause of bilateral macronodular adrenal hyperplasia with diet-induced Cushing's syndrome. This rare disease affects the two adrenal glands located above the kidneys and causes an overproduction of cortisol, a steroid hormone whose excess has harmful consequences for the body . Researchers were able to determine the molecular explanation for the occurrence of this disease 30 years after its initial description.
What are the molecular and genetic characteristics that distinguish patients with critical forms of COVID-19 – and particularly acute respiratory distress syndrome (ARDS)? Researchers have investigated the biological and genomic data of a targeted cohort of young patients. Patients hospitalized in intensive care with ARDS were compared with COVID-19 patients hospitalized in a non-critical care ward. As part of a Franco-US collaboration, the scientists have succeeded in identifying a...
