Inserm Unit 915 “Institut du thorax”, Nantes
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Skeletal muscle wasting, a process commonly associated with aging but also seen with various chronic diseases (obesity, cancer, kidney failure), situations of immobilization (accidents, post-operative periods) or prolonged weightlessness (astronauts), strongly impacts quality of life. Researchers from the Cardiovascular, Metabolism, Diabetology and ...
A national trial on membranous glomerulonephritis in 80 patients was coordinated by Prof. Pierre Ronco, of the Department of Nephrology and Dialysis at Tenon Hospital AP-HP, of the Inserm Unit “Rare and common kidney diseases, matrix remodelling and tissue repair”  and ...
“The Rho exchange factor Arhgef1 mediates the effects of angiotensin II on vascular tone and blood pressure”
Christophe Guilluy1,2,8, Jérémy Brégeon1,2,8, Gilles Toumaniantz1,2, Malvyne Rolli-Derkinderen1,2, Kevin Retailleau3, Laurent Loufrani3, Daniel Henrion3, Elizabeth Scalbert4, Antoine Bril4, Raul M Torres5, Stephan Offermanns6, Pierre Pacaud1,2 & Gervaise Loirand1,2,7
(1)Inserm, U915, Nantes, France.
(2)University of Nantes, l’institut du thorax, Nantes, France.
(3)Inserm, U771 and CNRS UMR6214, Faculté de Médecine Angers, France.
(4)Institut de Recherches Servier, Suresnes, France.
(5)Integrated Department of Immunology, University of Colorado, Denver, Colorado, USA.
(6)Department of Pharmacology, Max-Planck-Institute for Heart and Lung Research, Bad Nauheim, Germany.
(7)CHU Nantes, l’institut du thorax, Nantes, France.
(8)These authors contributed equally to this work.
Nature Medicine, 4 février 2010