Several observational and clinical research projects on the monitoring of symptomatic pregnant women, monitoring of children with malformation of the nervous systems or born of infected mothers, construction of biobanks of biological specimens and samples, assessment of the penetration of the virus in populations, and mathematical modelling of its dynamics, have already begun. Teams working in the neuroscience area have also been assembled to begin projects on this theme in a coordinated manner, given the neurotropic nature of the Zika virus.
More specifically, projects strongly involving the French Departments in the Americas are concerned with the following:
In terms of diagnostics, the aim is to rapidly develop a reliable method at individual and population scale, particularly aimed at pregnant women and newborns, taking into account the variety of pathogens, particularly arboviruses, that co-circulate in countries where the Zika virus epidemic is rife.
Based on these initial elements, Inserm and its partners in the Aviesan alliance have responded to a European call for proposals. For the Aviesan partners, this means:
Nadine Dragin, a researcher from an Inserm/UPMC/CNRS/AIM team codirected by Sonia Berrih-Aknin and Rozen le Panse at the Institute of Myology, based at Pitié-Salpêtrière Hospital, AP-HP, has demonstrated the central role of AIRE, a key factor in immune tolerance, in the unequal ...
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(Français) Exposition in utero aux perturbateurs endocriniens : les leçons du distilbène
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