Tackling HIV continues to be a major public health challenge, mainly because the persistence of viral reservoirs means that people living with HIV need to take lifelong antiretroviral treatment. But some individuals, known as "post-treatment controllers," are able to maintain an undetectable viral load even after stopping treatment. Scientists from the Institut Pasteur, Inserm and the Paris Public Hospital Network (AP-HP) identified specific immunogenetic characteristics in a group...
Tackling HIV continues to be a major public health challenge, mainly because the persistence of viral reservoirs means that people living with HIV need to take lifelong antiretroviral treatment. But some individuals, known as "post-treatment controllers," are able to maintain an undetectable viral load even after stopping treatment. In a study funded by ANRS Emerging Infectious Diseases (ANRS MIE), scientists from the Institut Pasteur, Inserm and the Paris Public Hospital...
Food additive mixtures are an everyday feature of our diets, especially through ultra-processed foods. In a new study, researchers from Inserm, INRAE, Sorbonne Paris Nord University, Paris Cité University and Cnam, as part of the Nutritional Epidemiology Research Team (CRESS-EREN), examined the possible links between exposure to mixtures of commonly consumed food additives and the onset of type 2 diabetes. They analysed the health data of over 100 000 adults...
Many cases of sudden cardiac death could be avoided thanks to artificial intelligence. As part of a new study to be published in European Heart Journal, a network of artificial neurons imitating the human brain was developed by researchers from Inserm, Paris Cité University and the Paris public hospitals group (AP-HP), in collaboration with their colleagues in the USA.
Macrophages, key cells of the immune system, play a central role in cleaning the body by ingesting and destroying pathogens (bacteria, viruses, etc.) and damaged cells. Scientists from Inserm, CNRS and the University of Bordeaux, in collaboration with international teams, reveal that this well-known role is accompanied by another surprising ability: in order to support their activity and metabolism, macrophages are capable of sourcing nutrients directly via the breakdown...
Human cognitive biases can particularly affect decision-making when speed is of the essence, such as when lives are at stake in a medical emergency. A research team from Inserm and the University of Bordeaux has tested an advanced method of generative artificial intelligence (AI) , trained with data from patient records corresponding to 480 000 entries to the Bordeaux University Hospital Emergency Department.
Amyotrophic Lateral Sclerosis (ALS), Charcot's disease, or Lou Gehrig's disease is a severe neurodegenerative disease that leads to progressive paralysis of muscles involved in voluntary movement. To date, no curative treatment exists. The disease is typically fatal within three to five years of onset. Researchers from Inserm and University of Strasbourg, at the Center for Biomedical Research, have made progress in understanding the mechanisms underlying ALS. In a new...
Widely used by the food industry, emulsifiers – a type of food additive – are found in many everyday foods. Given their omnipresence in our diet, the health effects of their consumption have become a real public health issue. Benoit Chassaing, Inserm Research Director and leader of the Microbiome-Host Interactions team at Institut Pasteur (Inserm/Université Paris Cité/CNRS), has previously shown that by acting directly on our gut microbiota, these additives...
MASH, formerly known as NASH, is a serious chronic liver disease that affects around 4-6% of the world's adult population. A new study reveals that, contrary to what was previously thought, there is not just one form of MASH, but two. They differ both in terms of biological characteristics and progression. One is of genetic origin, while the other is the consequence of metabolic disorders. This discovery, made at...
In celebration of its 60th anniversary, Inserm is emphasizing its scientific collaboration with the United States and Canada. This privileged and fruitful relationship with North America will be highlighted during a day of scientific and institutional exchanges on October 29, 2024, at the French Embassy in Washington, DC. The event will be attended by Professor Didier Samuel, President and CEO of Inserm, along with representatives from numerous partner institutions....
