A French and English team (AP-HP, Inserm, UPEC, CEA/Mircen, Oxford Biomedica, Cambridge University) has conducted a clinical phase 1/2 gene therapy study among patients suffering from an evolved form of Parkinson’s disease. Fifteen patients were able to benefit from this new treatment, which involves injecting a vector expressing the genes of three enzymes that are essential for the biosynthesis of dopamine, which is lacking in Parkinson’s disease. Thanks to...
French-Swedish team including researchers from CNRS, Inserm and the Université Claude Bernard Lyon 1 (Unité Inserm 855 “Nutrition et Cerveau”) has succeeded in elucidating this mechanism, which involves the intestinal flora and the ability of the intestine to produce glucose between meals.
The CHILD-INNOVAC European research programme, coordinated by Inserm, has enabled the development of an innovative vaccine that can be administered intranasally, to combat pertussis, which has shown a resurgence in developed countries in recent years. The research consortium, headed by Camille Locht, Director of the Centre for Infection and Immunity of Lille (a joint Unit involving Inserm, CNRS, Institut Pasteur de Lille and University of Lille Nord de France),...
Two INSERM research teams led by Pier Vincenzo Piazza and Giovanni Marsicano (INSERM Unit 862 "Neurocentre Magendie" in Bordeaux) recently discovered that pregnenolone, a molecule produced by the brain, acts as a natural defence mechanism against the harmful effects of cannabis in animals.
For the first time, scientists from the Institut Pasteur and Inserm have demonstrated the key role played by a particular molecule in intestinal infection.
The European EUCelLEX Project (Cell-based regenerative medicine: new challenges for EU legislation and governance), coordinated by Inserm for a three-year period, funding to the tune of €500,000 from the European Union.
Professor André Syrota, Inserm Chief Executive, and Professor Peretz Lavie, President of Technion, will sign the agreement to create a new Associated International Laboratory (AIL) on 17 December 2013. This artificial 'electronic nose' project brings together Inserm Unit 999 'Pulmonary Hypertension' and the Russell Berrie Nanotechnology Institute Chemical Engineering department, directed by Professor Hossam Haick.
The new report, “Maternal Mortality in France,” coordinated by Inserm Unit U953, Epidemiological Research Unit on Perinatal Health and Women’s and Children’s Health, announces a reduction in the rate of mortality due to postpartum haemorrhage—the leading cause of maternal mortality in France—for the 2007-2009 data compared to 2004-2006.
A phase I/II gene therapy clinical trial for children suffering from Sanfilippo B syndrome, a rare genetic disease, enrolled a first patient in October of this year.
In the fruit fly Drosophila and zebrafish, mechanical strain may activate the genetic cascade that initiates the formation of the future organs during embryogenesis. A discovery made by Emmanuel Farge (Inserm Research Director at Institut Curie) and his staff might explain the emergence of the first complex organisms more than 570 million years ago.
The annual Inserm awards ceremony will take place on Monday 2 December at the Collège de France. On this occasion, eight prizes will be awarded to women and men who contribute daily to the scientific excellence of the Institute. Stanislas Dehaene will be awarded the Inserm Grand Prix for his body of work on consciousness, Ogobara Doumbo will receive the International Prize for his research on malaria, and Daniel Louvard...
