Omega-3 fatty acids are essential, necessarily supplied by the diet and indispensable to brain development. Scientists have focused in particular on the impact of the maternal diet during gestation and lactation on the brain development of their offspring. They have thus shown for the first time in mice how an insufficient intake of omega-3 in the mother can alter the development of neuronal networks in the offspring, causing memory...
Dysfunctions of ion channels - or channelopathies - in the brain are today associated with more than 30 neurological diseases such as epilepsy or cerebellar ataxias. A study conducted at the Brain Institute (Sorbonne University / Inserm / AP-HP / CNRS) identified a new cerebral channelopathy originating from dominant mutations in the KCNN2 gene, encoding the SK2 ion channel.
Diet is believed to play a role in triggering intestinal inflammation that can lead to the development of certain conditions, such as Crohn's disease. Researchers from Inserm, CNRS and Université de Paris have shown that the emulsifiers present in many processed foods could have a harmful impact on specific bacteria in the gut microbiota, leading to chronic inflammation.
Type 2 diabetes is a risk factor for the development of a severe form of Covid-19. Identifying the immune- and inflammatory markers associated with these severe forms of the disease in this patient population would enable earlier and more appropriate care.
A new therapeutic target for type 2 diabetes has recently been identified by researchers from Inserm and Université de Strasbourg, in collaboration with several European hospitals.
Inserm was tasked by France’s Health Directorate with conducting a Collective Expert Review in order to take stock of the scientific knowledge on fibromyalgia in adults, and also to explore the potential existence of a similar syndrome in children and adolescents. The objective was also to recommend measures and establish research priorities in order to better understand fibromyalgia and improve patient care.
A study is showing for the first time that tobacco consumption, even when stopped before pregnancy, can have an impact on the placenta. Smoking not just during but also before pregnancy leads to epigenetic modifications (DNA methylation) which could have consequences on its course.
The 2019 Nobel Prize was awarded on Monday, October 7
Today, COVIREIVAC opens the registration process for volunteers to participate in the first large-scale clinical trials in France.
A research team from Inserm, Lille University, Lille University Hospital, CNRS, and the Institut Pasteur of Lille, as part of the Lille Immunity and Infection Center, is developing a new vaccine against whooping cough. En utilisant la bactérie entière mais génétiquement modifiée pour supprimer sa toxicité, les chercheurs espèrent pallier les défauts d’efficacité du vaccin actuel en induisant une réponse immunitaire durable et en bloquant la transmission bactérienne entre...