A study, aimed at identifying the risk factors for the severity of COVID-19 in patients with multiple sclerosis in France, was carried out by teams from the neurology department of the Pitié-Salpêtrière hospital AP -HP, from the Brain Institute (Inserm / CNRS / Sorbonne University) at the Pitié-Salpêtrière hospital AP-HP, from Sorbonne University and the neurology service of the Strasbourg CHU.
Les deux bras testant la combinaison lopinavir/ritonavir avec ou sans interféron bêta sont arrêtés dans les essais cliniques Solidarity et Discovery. Compte tenu de la nature adaptative des deux essais, une réflexion est en cours sur l'évolution du protocole. Des publications dans des journaux internationaux à comité de lecture sont en préparation concernant tant l'évaluation de l'hydroxychloroquine que du lopinavir/ritonavir.
Depuis plusieurs années, un débat portant sur l’efficacité contre le paludisme de divers produits non pharmaceutiques à base d’Artemisia agite la communauté scientifique. Il fait son retour avec l'épidémie de Covid-19.
In a study published in March 2020 in the journal EClinical Medicine, Prof. Gérard Lina’s team suggests simple measures to put in place for better tampon use during menstruation.
While genetic predisposition is a major factor in the risk of developing age-related dementia, and Alzheimer's disease in particular, environmental factors such as diet also have an important role to play. Thanks to the 12-year follow-up of nearly 2,800 French people over the age of 65, a research team has sought to understand the impact of meals high in sugars (simple sugars and refined carbohydrates) on the risk of...
Developing an effective and safe vaccine is one of the priority objectives in the fight to contain the COVID-19 pandemic. At Inserm, a dozen teams are involved in vaccine research projects. In particular, three initiatives have recently been selected by France’s Ministry of Higher Education, Research and Innovation on the advice of the COVID-19 Analysis, Research and Expertise Committee (CARE) and Inserm's REACTing consortium, in order to receive...
Des investigateurs français de l’Institut médico-légal de Paris, de l'Inserm, du service de radiologie de l’hôpital Sainte-Anne/GHU Paris, du département d’anesthésie-réanimation des hôpitaux de l’AP-HP Saint-Louis et Lariboisière, d’Université de Paris, et du CNRS ont fait l’hypothèse que les arrêts cardiaques en dehors de l'hôpital pendant le pic de la pandémie de Covid-19 pourraient être en partie dus à des embolies pulmonaires massives. Le détail de ces travaux a...
Inflammations of the intestine affect many patients, often with reduced therapeutic prospects. The role of iron in these inflammatory processes is increasingly well documented, opening up new avenues of treatment. A collaborative study shows that the hormone that regulates iron levels in the body is produced by immune cells during inflammation of the intestine, and that it helps repair damage to the intestinal mucosa.
Persistently engaging in negative thinking patterns may raise the risk of Alzheimer’s disease, finds a new UCL-led study.
Until now considered highly promising in the fight against aging, the therapeutic strategy of eliminating the senescent cells that accumulate in the body is being challenged by the team of Dmitry Bulavin, Inserm researcher at the Institute for Research on Cancer and Aging of Nice (Inserm/CNRS/Université Côte d’Azur).
