A team of scientists led by Inserm Research Director Basile Chaix at the Pierre Louis Institute of Epidemiology and Public Health (Inserm/Sorbonne Université) studied the impact of these parameters on exposure to black carbon, an air pollutant produced by road traffic.
Reducing fine particle mortality in a conurbation by two-thirds could be achieved at a cost that is much lower than the value of the societal and economic benefits obtained, according to a study by a multidisciplinary team from CNRS, INSERM, INRAE, Grenoble Alpes University (UGA) and Atmo Auvergne-Rhône-Alpes. The study identifies specific public policies that could achieve health objectives set by local decision makers, as well as their expected...
Multiple myeloma is a cancer of the bone marrow, with a life expectancy of less than 5 years post-diagnosis. While studying a neglected tropical disease, Buruli ulcer, researchers from the Institut Pasteur and Inserm discovered a novel therapeutic target for multiple myeloma that could allow to bypass this resistance.
France has one of the world’s highest levels of cannabis use, with around 40% of 17-year-olds reported to have used it in the previous year. New findings indicate that those having used cannabis are more likely to experience a period of unemployment later, especially if they were under 16 when they started.
Scientists had previously shown in mice that the presence of emulsifiers in many processed foods could promote intestinal inflammation. In a new study, the same team has shown in healthy human volunteers that carboxymethylcellulose (CMC), a widely used food emulsifier, affects the intestinal environment by altering the composition of the microbiota.
Why are children less susceptible than adults to critical forms of COVID-19? A number of interesting avenues are emerging, notably suggesting differences in immune response following SARS-CoV-2 infection. In a new study, researchers have shown that the interferon response, which is part of the innate immune response, differs according to the age of the patient.
The French health authorities recommend that all adults over 18 years of age perform a booster injection with a MRNA to ensure maximum and prolonged vaccine protection. The COVIBOOST trial is designed to study the immune response of the two candidates based recombinant protein vaccine associated with an adjuvant developed by Sanofi Pasteur and GSK and that of a 3 rd dose of the Pfizer-Biontech vaccine.
Des chercheurs ont montré que la substitution d’un seul nucléotide dans le gène qui code pour le récepteur nicotinique de l'acétylcholine peut entrainer des modifications fonctionnelles des cellules des voies aériennes et conduire à des symptômes similaires à ceux de la BPCO, indépendamment du tabagisme.
In this year 2021, still marked by COVID-19, Inserm’s workers have remained mobilized to advance biomedical research and pursue their efforts across all areas of health research. To honor this collective endeavor, Inserm has awarded its 2021 Prizes to five people whose quality of work bears witness to the scientific excellence of the Institute’s research.