Tuesday May 1 is World Asthma Day - a day to educate and raise public awareness to improve the diagnosis and treatment of asthma.
With the genome editing CRISPR-case.9 technique, researchers at INSERM, the hospital Necker Children-AP-HP, and Université Paris Descartes in the Institute Imagine managed to reactivate a gene that may improve the appearance of red blood cells of patients with hemoglobinopathies such as sickle cell anemia and beta-thalassemia. The teams Annarita Miccio, Inserm researcher, Prof. Marina Cavazzana AP-HP and Isabelle André-Schmutz, Inserm researcher show this new avenue of research and treatment...
In an article in the New England Journal of Medicine published on April 19, the intermediate results of a clinical trial (HGB-205) led by Pr. Marina Cavazzana and her teams at the Necker-Enfants malades hospital AP-HP in collaboration with the Imagine Institute (AP-HP/Inserm/Paris Descartes University) as well as those of an international multicenter trial (HGB-204) conducted in the United States, Thailand and Australia, show that gene therapy is effective...
How can we preserve renal function in people with a chronic kidney disease? Can dialysis be avoided or delayed? To answer these questions and many others, Inserm and Université Paris-Sud have set up the CKD-REIN1 cohort study, led by Bénédicte Stengel. Today it has produced its first results. According to the study, conducted with more than 3,000 patients, several priorities may improve the management of kidney disease. These priorities...
The thirteenth annual World Immunization Week will take place from April 23 to 29, 2018. The campaign, created by the World Health Organization (WHO), undertakes to raise awareness about the stakes of vaccine protection.
The respective classifications of the European Patent Office (EPO) and France's National Industrial Property Institute (INPI), which have just published their annual rankings for 2017, have confirmed Inserm's ability to innovate. Inserm placed first among patent applicants in the pharmaceutical sector for the second year in a row, yet again leading the rankings of European applicants in this sector, ahead of both industrial manufacturers and academic institutions. Furthermore, the...
One of the major challenges identified by the WHO in efforts to eradicate the hepatitis C virus (HCV) is the diagnosis of chronic cases that are generally asymptomatic. Major progress is required for new diagnostic techniques that can be "decentralized", in other words accessed by populations and countries with limited resources. Scientists from the Institut Pasteur and Inserm, in collaboration with the company genedrive, have developed and validated a...
À l’occasion de la journée mondiale Parkinson, une étude publiée dans le Bulletin épidémiologique hebdomadaire (BEH) suggère un risque plus important de développer la maladie chez les personnes qui vivent dans des cantons agricoles.
Accelerate artificial intelligence research to benefit health: such is the shared objective underpinning the agreement signed by Inserm and the start-up Owkin, specialized in machine learning applied to biological and medical research. The tools developed by Owkin, combined with the mass of health data either produced or used by Inserm, will lead to the development of disruptive innovations unprecedented in the field of medical and clinical research.
What if immune system efficacy against cancerous cells could be reinforced by a diet in which calories are not reduced but nutrients are precisely determined? This what Inserm researchers from Université Côte d’Azur, through a study of the effects of restrictive diets on tumor growth in mice, have been exploring. They have observed that a low-protein diet restricts tumor development by increasing immune response. The findings, to be published...
Living beings are able to integrate and identify relevant sensory information, such as smells, sounds or light, in order to regulate how they behave in the presence of potential danger. This is called context discrimination. Inserm researchers based at Neurocentre Magendie in Bordeaux have recently discovered which neurons are implicated in this phenomenon and where they are located. Good news for sufferers of post-traumatic stress disorder in whom context...
