Calyxis in Niort and the Inserm-Université de Bordeaux Population Health Research Center have published the findings of their study on the mental health impacts of lockdown in the journal Globalization and Health. Anxiety, depression, and self-rated mental health saw marked deteriorations in the MAVIE cohort, particularly in women, young people, elderly people, and those with less than 30 m2 of living space
Certains pesticides utilisés en Europe sont suspectés d’avoir des effets néfastes sur la santé humaine. Ils provoqueraient des perturbations hormonales et auraient également des propriétés carcinogènes, déjà observées en milieu professionnel. Le lien entre l’exposition à ces pesticides via l’alimentation et le cancer du sein dans la population générale est encore peu étudié.
What are the factors predicting progression to severe forms of COVID-19? One year into the pandemic, this question remains a key research subject, and one that scientists from Inserm and Université de Paris decided to explore further by studying the link between viral kinetics and disease progression.
The Phase 3 clinical trial of a COVID-19 vaccine is to be launched via Covireivac, a platform set up under the auspices of Inserm and the university hospitals to centralize COVID-19 vaccine trials in France. Janssen, the pharmaceutical division of the Johnson & Johnson group, has obtained the authorizations[1] needed for ENSEMBLE 2, a trial evaluating the efficacy and safety of vaccine candidate Ad26.COV2.S in the prevention of COVID-19...
Elderly women are currently at a higher risk than men of developing dementia, particularly Alzheimer's disease. A phenomenon that could partially be explained by inequalities in access to education between the sexes during the first half of the 20th century. Researchers from Inserm and Université de Paris, in collaboration with University College London, have shown that certain cognitive capacities have improved in women over recent generations, and that this...
The Discovery trial was originally launched in March 2020 by Inserm to evaluate possible treatments for Covid-19. On January 13th, 2021, the Discovery Europe trial Data Safety Monitoring Boards (DSMB) evaluated an interim report based on 776 patients of whom 389 received remdesivir and 387 received standard of care. The efficacy of the treatment was evaluated after 15 days and measured on the WHO-7-point ordinal scale. As a result...
Pour faire face à la pandémie de Covid-19, mieux comprendre le virus et accompagner la prise en charge des maladies, les scientifiques de l'Inserm sont plus que jamais mobilisés.
A study by Inserm and Dijon University Hospital based on French nationwide data on around 130,000 patients hospitalized for either COVID-19 or seasonal influenza shows that the mortality rate among those admitted for COVID is three times higher than that of seasonal influenza.
Back at the start of the pandemic, Inserm, through its REACTing consortium, set up Discovery: a European clinical trial to evaluate the efficacy of four antiviral drugs repurposed for the treatment of patients hospitalized with COVID-19 (remdesivir, hydroxychloroquine, lopinavir and interferon beta-1a). In parallel, the World Health Organization (WHO) set up Solidarity, a major consortium of clinical trials also aimed at testing the efficacy of these four treatments. Discovery...
Inserm was tasked by France’s Health Directorate with conducting a Collective Expert Review in order to take stock of the scientific knowledge on fibromyalgia in adults, and also to explore the potential existence of a similar syndrome in children and adolescents. The objective was also to recommend measures and establish research priorities in order to better understand fibromyalgia and improve patient care.
A study is showing for the first time that tobacco consumption, even when stopped before pregnancy, can have an impact on the placenta. Smoking not just during but also before pregnancy leads to epigenetic modifications (DNA methylation) which could have consequences on its course.
