Results 11 - 20on 31 for [ fertility ]
- 2019
-
Press releases - 30.04.2019
Fertility and endometriosis: a research update from Inserm
Today, around 1 in 8 couples seek help because they are struggling to conceive. Infertility has therefore become a public health problem, and the scientific community is rallying in response.
- 2018
-
Press releases - 23.07.2018
In Mice, Exposure to Chlordecone has Transgenerational Effects on Sperm Production
A study coordinated by Inserm researchers at the Research Institute for Environmental and Occupational Health in Rennes shows that exposing pregnant mice to chlordecone affects the third generation of their male progeny
-
Press releases - 17.05.2018
Towards Understanding the Origin of the Most Common Form of Female Infertility
Des chercheurs de l’Inserm et de l’Université de Lille, ont découvert que le plus fréquent des troubles de la fertilité féminine – le syndrome des ovaires polykystiques (SOPK) – serait causé par la surexcitation de neurones cérébraux. La coupable : une hormone produite par les ovaires, appelée « Hormone anti-müllerienne» (AMH), suproduite chez les femmes souffrant d’un SOPK. Les travaux de l’équipe chez la souris montrent l’importance de l’exposition in utero à des taux anormalement élevés d’AMH dans l’occurrence de la maladie. Ces résultats parus dans Nature Medicine ouvrent la voie à de nouveaux concepts sur l’origine embryonnaire de la maladie ainsi qu’à de nouvelles pistes pour l’élaboration d’un traitement.
- 2017
-
Press releases - 09.08.2017
Testicular macrophages are guardians of fertility
The origin, development, and characteristics of two types of testicular macrophage have been described by a CNRS team at the Centre d’Immunologie de Marseille-Luminy (CNRS / INSERM / Aix-Marseille University). To elucidate the nature of these immune cells, the researchers used a novel cell tracing method. Their findings were published on August 7, 2017, in the Journal of Experimental Medicine, and are of fundamental importance. They may help understand certain kinds of infertility in men and find new treatments for them.
-
Press releases - 27.06.2017
Opening of medically assisted procreation to female couples and single women
Today, the National Consultative Ethics Committee (CCNE) has decided to open up medically assisted procreation (MAP) to female couples and single women in France.
In a report released on June 19, the National Academy of Medicine has advocated egg preservation for women who wish to do so. -
What's on? - 27.06.2017
Opening of medically assisted procreation to female couples and single women
Today, the National Consultative Ethics Committee (CCNE) has decided to open up medically assisted procreation (MAP) to female couples and single women in France. In a report released on June 19, the National Academy of Medicine has advocated egg preservation for women who wish to do so. Medically assisted procreation (MAP) involves manipulating an egg and/or […]
-
Press releases - 09.06.2017
We’re all a bit Neanderthal… or are we?
A study conducted by Inserm researchers at the Research Institute for Environmental and Occupational Health (Irset)[1] has shown that natural selection has “purged” our bodies of many of the traces of our ancient Neanderthal and Denisovan cousins in the genes responsible for the genetic mixing essential to reproduction. The researchers have shown that the genes expressed during meiosis in the cells that produce gametes (reproductive cells) are strongly deficient in genetic variations of Neanderthal origin that were the result of the interbreeding between Homo sapiens and Homo neanderthalensis. These results have been published in Molecular Biology and Evolution.
- 2016
-
Press releases - 07.10.2016
Rituximab effective in the treatment of membranous glomerulonephritis
A national trial on membranous glomerulonephritis in 80 patients was coordinated by Prof. Pierre Ronco, of the Department of Nephrology and Dialysis at Tenon Hospital AP-HP, of the Inserm Unit “Rare and common kidney diseases, matrix remodelling and tissue repair” [1] and Pierre and Marie Curie University, and by Dr Karine Dahan, of the Nephrology Day Hospital at Tenon Hospital AP-HP. This serious autoimmune disease is the most common cause of nephrotic syndrome in adults. In 30% of cases, it progresses to very severe renal failure. Conducted in collaboration with Prof. Tabassome Simon, from the Department of Clinical Pharmacology and East Paris Clinical Research Centre at Saint Antoine Hospital, AP-HP, this trial shows, for the first time, the efficacy and safety of rituximab in treating the disease.
-
Press releases - 29.09.2016
Zika virus found inside spermatozoa
Recent work has shown that Zika virus persists in semen for up to 6 months after infection[1]. In a correspondence published in The Lancet Infectious Diseases, the researchers, in addition to confirming its long persistence in semen (in this case for more than 130 days, i.e., over 4 months), reveal the presence of the virus even within spermatozoa. This work results from collaboration between researchers from Inserm, CNRS, and academic practitioners from University Toulouse III – Paul Sabatier and Toulouse University Hospital.
-
Press releases - 02.05.2016
Control of fertility: a new player identified
Individual small RNAs are responsible for controlling the expression of gonadoliberin or GnRH (Gonadotropin-Releasing Hormone), a neurohormone that controls sexual maturation, the appearance of puberty, and fertility in adults. This has just been demonstrated by the “Development and Plasticity of the Neuroendocrine Brain” team led by Vincent Prévot, Inserm Research Director (Jean-Pierre Aubert Research Centre, Lille). The involvement of microRNAs, transcribed from DNA, occurs around birth, and marks a key step in postnatal development. Failure of these microRNAs to act leads to the disruption or even total cessation of GnRH production by the hypothalamic neurons that synthesise it, and hence to infertility. In the most serious cases, sterility may result. Details of this work in mice are published in the 2 May 2016 issue of the journal Nature Neuroscience.