- 2013
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Press releases - 19.02.2013
(French) Infection VIH par voie sexuelle : élucidation de mécanismes-clé chez l’homme
The HOMAGE (Heart OMics in AGEing) project, coordinated by the French National Institute of Health and Medical Research (INSERM), has been awarded a grant by the European Commission for a 6 year period. The project aims to identify and validate specific biomarkers of heart failure in order to prevent the development of the disease affecting elderly population. 17 research groups from 10 countries will collaborate to investigate new ways of preventing heart failure. The project will use an innovative ‘omic-based’ approach which investigating simultaneously a huge amount of genes, proteins and metabolites. The 17 partners will meet at Nancy on February 22nd for the kick off meeting of HOMAGE.
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News in brief - 19.02.2013
Advances in Friedreich’s Ataxia
Friedreich’s ataxia is a rare, serious and developing neurodegenerative condition that emerges at adolescence. Those affected suffer from difficulties in coordinating voluntary movements (ataxia). This is the commonest of the hereditary ataxias of genetic origin and occurs due to a mutation of the fraxatin gene which causes a protein deficiency. The team headed by Alexandra […]
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Press releases - 18.02.2013
HOMAGE – Overcoming Heart Failure, an European challenge
The HOMAGE (Heart OMics in AGEing) project, coordinated by the French National Institute of Health and Medical Research (INSERM), has been awarded a grant by the European Commission for a 6 year period. The project aims to identify and validate specific biomarkers of heart failure in order to prevent the development of the disease affecting elderly population. 17 research groups from 10 countries will collaborate to investigate new ways of preventing heart failure. The project will use an innovative ‘omic-based’ approach which investigating simultaneously a huge amount of genes, proteins and metabolites. The 17 partners will meet at Nancy on February 22nd for the kick off meeting of HOMAGE.
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What's on? - 18.02.2013
Fertility problems – what we know and our lines of research
Infertility affects more and more couples. The data on infertility inFranceis only partial or uncertain. So we must create a fertility monitoring system, based principally on repeated, specific surveys and we must systematically include suitable questions on demographic or epidemiologic surveys used to study reproduction or contraception. It is estimated that around 15% to 20% […]
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Press releases - 15.02.2013
History of stroke and coronary heart disease – a fatal combination
The cardiology service team at the Hôpital Bichat and the Mixed INSERM Unit 698 (AP-HP, Université Paris Diderot), in collaboration with international teams of researchers, studied a cohort of patients suffering from coronary disease. The study showed that those patients with a history of stroke or transient ischæmic attack (TIA) are not only at higher risk of cardio-vascular episodes but also of haemorrhagic events, stressing the therapeutic challenge involved in treating such patients.
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Press releases - 13.02.2013
The efficacy of certain anti-cancer vaccines depends on how they are administered
The therapeutic efficacy of certain anti-cancer vaccines depends on how they are administered. This is what the team of researchers headed by Eric Tartour at the Paris-Centre de recherche Cardiovasculaire (Université Paris Descartes, INSERM Unit 970 PARCC, AP-HP), in collaboration with researchers from the CNRS , have just demonstrated.
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Press releases - 13.02.2013
“Simplified” brain lets the iCub robot learn language
The iCub humanoid robot on which the team directed by Peter Ford Dominey, CNRS Director of Research at Inserm Unit 846 known as the “Institut pour les cellules souches et cerveau de Lyon” [Lyon Institute for Stem Cell and Brain Research] (Inserm, CNRS, Université Claude Bernard Lyon 1) has been working for many years will now be able to understand what is being said to it and even anticipate the end of a sentence. This technological prowess was made possible by the development of a “simplified artificial brain” that reproduces certain types of so-called “recurrent” connections observed in the human brain.
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What's on? - 12.02.2013
The development of mortality due to pleural mesothelioma in France
The French health watch institute (InVS) worked in partnership with the Inserm unit “Epidemiological Center for Mortality by Medical Causes” to publish the results of models they had produced showing the development of mortality due to pleural mesothelioma in France, based on the latest data available in France. Models had been produced at the end […]
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Press releases - 11.02.2013
Cancer du col de l’utérus : première résolution 3D d’une oncoprotéine du virus à papillome humain
Des chercheurs strasbourgeois du laboratoire Biotechnologie et signalisation cellulaire de l’École Supérieure de Biotechnologie de Strasbourg (CNRS/Université de Strasbourg) et de l’Institut de génétique et de biologie moléculaire et cellulaire (CNRS/Université de Strasbourg/Inserm) ont résolu, pour la première fois, la structure tridimensionnelle d’une oncoprotéine majeure, impliquée dans la prolifération cellulaire et à l’origine du développement du papillomavirus humain. Celui-ci, de type 16 (HPV 16), est le plus dangereux de ces virus, responsable des cancers du col de l’utérus. Ces travaux, publiés le 8 février 2013 dans Science, devraient permettre l’identification et l’amélioration de médicaments bloquant les activités tumorigènes de la protéine.
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Press releases - 07.02.2013
Treatrush (TreatRetUsher): combating Usher Syndrome blindness – European collaboration in the service of a rare disease
Comment la recherche sur le syndrome de Usher – handicap héréditaire particulièrement invalidant, portant atteinte aux deux sens majeurs, l’audition et la vision – a-t-elle franchi une étape majeure dans la compréhension des mécanismes à l’origine de la rétinopathie pigmentaire ? Comment est-elle parvenue à améliorer le diagnostic clinique et à développer le diagnostic moléculaire ? Comment prépare-t-elle les essais de thérapie génique de la rétinopathie du syndrome ? Les scientifiques regroupés au sein du projet européen TREATRUSH (TreatRetUsher) présentent les avancées qu’ils ont réalisées. Douze partenaires de 7 pays sont réunis au sein de ce réseau financé par la Commission Européenne et coordonné par l’Université Pierre et Marie Curie (UPMC).