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New phase of the Elfe study : an original study on learning in nursery school children !

In spring 2016, a new phase in the Elfe Child Cohort Study will take place in French nursery schools, with participation by middle-year teaching staff. Its objective: to collect information on early learning by children of approximately 5 years of age. It will hence be possible to analyse the manner in which children enter the various areas of learning provided by nursery schools, taking living conditions, family structures, and the child’s health and development into account.

This “School” component of the Elfe study calls for participation by teachers via playful exercises in the areas of reading and numbers, prepared by the researchers.

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(c) Fotolia

The place of the School survey in monitoring the Elfe child cohort

Elfe is the first French study devoted to monitoring children from birth to adult age, which addresses the many aspects of their development and socialisation from the social sciences, health and environment perspective. When it was launched at national level in 2011, over 18,000 children were enrolled in the cohort.

The Elfe study is an innovative source of data for the large-scale analysis of the relationship, at every age, between parent biography, family life, socioeconomic characteristics, and child-minding arrangements and the development of children’s cognitive and social abilities.

The most important data are collected by conducting regular surveys with parents. Direct input is also sought from the children at age three and a half during a home visit, where they do a drawing and play various visual and picture-matching games. By continuing to monitor children at approximately 5 years of age, the School survey will be invaluable in offering a comprehensive and multifactorial approach to the world of early childhood and nursery school.

More information at:

www.elfe-france.fr/enseignant

Seasonal epidemic diseases: surveillance continues

The Sentinelles network, developed by Inserm and Pierre and Marie Curie University (UPMC), is a national surveillance system made up of 1,300 general practitioners and about a hundred private paediatricians, which allows the creation of large databases for several diseases, for purposes of health monitoring and research.

The Sentinelles physicians collect information from their patients on 8 health indicators, and submit it via the Internet. Analysis of these data allows estimation of the weekly incidence rate for each indicator, so that changes in these indicators can be monitored on the territory in real time.

 

According to the Sentinelles network’s weekly bulletin of 16 December, cases of gastroenteritis are up slightly in metropolitan France. 110,500 new cases were seen during visits to general practitioners last week. The incidence rate, estimated at 171 cases per 100,000 inhabitants, is, however, below the epidemic threshold. At regional level, Limousin, Aquitaine and Auvergne observed the highest incidence rates.

Spread of chickenpox remains moderate on the territory, with 22 cases per 100,000 inhabitants, with the most severely affected foci to be found in Picardy, Upper Normandy and Poitou-Charentes. For influenza, the incidence rate is well below the epidemic threshold.

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Fresh insight into the causes of infant and perinatal mortality in the Seine-Saint-Denis district

In 2012, the Île-de-France Regional Health Agency initiated a regional project aimed at Reducing Infant and Perinatal Mortality (RéMI). This initiative was primarily focused on Seine-Saint-Denis, a district characterised by excess infant mortality (death before one year of age) and perinatal mortality (foetal deaths and deaths in the first week of life). The 2 research reports ordered by the Agency under this initiative—including one prepared by Inserm, and officially submitted to its Director General yesterday—bring new clarity to the situation in the department.

The audit has made it possible to identify risk factors associated with the women’s personal situations: 50% of them were overweight or obese. 7% did not have access to Social Security at the start of pregnancy, and 9% were in receipt of State Medical Aid (AME), or were in a scheme for access to urgent care.

The expert reports on the deaths also underline that for three-quarters of them, deviations from good practice were observed in the care of the pregnant women.

33% of the deaths were judged potentially or probably avoidable, by acting on one or more of these deviations from good practice

Given this observation, ARS is launching 3 workshops bringing together professionals and those involved in perinatal care in Seine-Saint-Denis, which will run from November 2015 until March 2016, based on these areas of reflection.

Launch of the influenza vaccination campaign

Monday 12 October saw the start of the annual vaccination campaign, which will continue until the end of January 2016. Last winter recalled the potential seriousness of influenza, which severely affected the most vulnerable populations (mainly people over the age of 65).

To better control the influenza epidemic, Inserm has created the Sentinelles network, an information system based on a network of 1,300 general practitioners distributed throughout metropolitan France. These “sentinel physicians” report cases of influenza, diarrhoea or chicken pox on a weekly basis.

In this way, the Sentinelles network and Inserm monitor the progression of influenza throughout the year, and are in a position to anticipate peaks at national level. The health authorities thus receive the maximum amount of information, which allows them to adapt their resources for the better protection and care of citizens.sentinelles

Nobel Prize in Chemistry 2015

The Nobel Prize in Chemistry 2015 goes to Tomas Lindahl, Paul Modrich and Aziz Sancar “for mechanistic studies of DNA repair.

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Tomas Lindhal, Paul Modrich et Aziz Sancar © Nobelprize.org

Read the press release

Tomas Lindahl received The Foreigner Prize of Inserm in 2008. See Thomas Lindahl, in an interview on the Inserm History website : “Tomas Lindahl, Prix Etranger 2008

The Nobel Prize in Chemistry 2015. Nobelprize.org. Nobel Media AB 2014. Web. 5 Oct 2015.

Nobel Prize in medicine 2015

The Nobel Prize in Physiology or Medicine 2015 was divided, one half jointly to William C. Campbell and Satoshi Ōmura “for thier discoveries concerning a novel therapy against infections caused by roundworm parasites” and the other half to Youyou Tu “for her discoveries concerning a novel therapy against Malaria”.

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William C. Campbell, Satoshi Ōmura et Youyou Tu © Nobelprize.org

Read the press release

The Nobel Prize in Physiology or Medicine 2015. Nobelprize.org. Nobel Media AB 2014. Web. 5 Oct 2015.

French women breastfeed for 4 months on average

According to the World Health Organisation (WHO), exclusive breastfeeding (children only receiving breast milk and no other food or drink) should last until the infant is 6 months old and partial breastfeeding should continue up to 2 years of age. A study conducted by Inserm Unit 1018 “Centre for Research in Epidemiology and Population Health”, and published by the InVs (French Institute for Public Health Surveillance) Bulletin Épidémiologique Hebdomadaire, shows that French women breastfeed for an average of 17 weeks, or just over 4 and a half months in total, and only exclusively for two months.

These data come from the ELFE study organised by Inserm, Ined and the French National Blood Service, which monitored over 18,000 children since 2011. One of the aims was to analyse the duration for full and partial breastfeeding and then determine the sociocultural, demographical and economical factors associated with breastfeeding duration.

Researchers have demonstrated that if breastfeeding duration among women is shorter than the time recommended by WHO, then this observation is particularly true for women under 30 who live alone and have a low level of education.

For the authors of the study “These findings support the need to change the image of breastfeeding and to devise a promotional strategy that targets young mothers with low income and education that are more likely stop breastfeeding early”.

Heatwave 2015: Be careful of the abnormally high death rate

From Tuesday 30th June, France will enter into an exceptional heatwave for this time of year.[1]. These remarkably high temperatures (around 40 °C) can have particularly harmful consequences on the health: tiredness, dehydration, heat stroke, respiratory, heart, metabolic problems, etc. If, for the most part, these inconveniences are minor, they are lethal in certain cases, particularly for the at-risk populations such as young children or the elderly.

France has already experienced an exceptional heatwave in 2003, responsible for a high death rate. The Inserm researchers at the Epidemiology Centre on the medical causes of death (CépiDc) have produced an estimate of the high death rate linked to this heatwave on a national and regional level.

The numbers from the study are available in the official report “Surmortalité liée à la canicule 2003 (High death rate linked to the 2003 heatwave

The official report prepared by the Inserm researchers in collaboration with the InVS from 2006 “Estimation de la surmortalité observée et attendue au cours de la vague de chaleur du mois de juillet 2006 (Estimation of the high death rate seen and predicted during the heatwave of July 2006)” is also available.

[1] France weather (Météo France) website « Vague de chaleur: vers des températures exceptionnelles pour un début juillet (Heatwave: exceptional temperatures for the start of July)»

Cases of tuberculosis in Limoges, what does this mean for vaccination?

While tuberculosis (BCG) vaccination is no longer mandatory in France, five new cases of tuberculosis were recorded in Limoges this week. This disease, far from having disappeared, causes 5,000 new cases of illness each year, and is responsible for 700 deaths. These latest cases have restarted the debate about vaccination:

Should we get vaccinated? Should we have our children vaccinated? How does a vaccine work? Does vaccination really protect us?

Against this background, Inserm researchers Annick Guimezanes and Marion Mathieu have replied as objectively as possible to the questions everyone wonders about in the 3rd popular science book in the Choc Santé collection: “Vaccination: Agression or Protection?”couverture2

In a clear and accessible style, drawing on the most recent advances in the area, it will enable everyone to better weigh the risks and benefits of vaccination.

 

BACCALAURÉAT 2015: D-1

Starting on Wednesday 17 June, nearly 700,000 candidates, from 13 to 93 years of age[1], will be taking the baccalauréat state examination.

These exam periods, often synonymous with stress and fatigue, are a tough ordeal for our mind and body. On the eve of the written examinations, your notification to attend, bag and piece of identification are all ready, but what about your memory? How do you boost it, and look after it? Is there still time to revise? Is there a specific diet that should be followed? How many hours’ sleep does the future graduate need to be in full possession of his/her faculties?

Joëlle Adrien, Inserm Research Director at Unit 1127, “Brain and Spinal Cord Institute (ICM)”, and Francis Eustache, Director of Inserm Unit – EPHE – UCBN 1077, “Neuropsychology and Functional Neuroanatomy of the Human Memory,” specialists in sleep and human memory, respectively, answer your questions.

[1] To find out more, visit the French National Ministry of Education website

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