Preeclampsia is a condition that affects the placenta during pregnancy and is dangerous for both the fetus and the mother. Scientists from the Institut Pasteur, Inserm and the CNRS have proposed a new therapy, tested in two rodent models, that corrects the defects identified in placental cells, and restores placental and fetal weight. The treatment […]
In a new study, researchers investigated a receptor found on male germ cells that produce gametes, their aim being to find out more about its role in chemotherapy-related infertility. Their findings pave the way for a better understanding of male infertility and the development of treatments to reduce the risk of sterility from chemotherapy.
The zebrafish is particularly studied in research laboratories due to its ability to regenerate its caudal fin. This study opens up new avenues for improving our understanding of the regeneration processes, with the aim of developing clinical applications in the field of regenerative medicine.
The team of the adult nephrology-renal transplantation department of the Necker-Enfants Malades AP-HP hospital, Inserm and the University of Paris has carried out work, coordinated by Prof. Guillaume Canaud, which opens up new perspectives. therapies for patients with lymphatic abnormalities linked to a mutation in the PIK3CA gene.
Teams of researchers studied the presence of self-reactive memory B lymphocytes before and after treatment with rituximab in adult patients with thrombocytopenia immunologic disease (ITP), a rare autoimmune disease. The results of this study show that a fraction of memory B lymphocytes self-reactive towards platelet antigenesist treatment with rituximab, persist in the spleen for several months and participates in relapses. The discovery of these cells could open up new...
Diet is believed to play a role in triggering intestinal inflammation that can lead to the development of certain conditions, such as Crohn's disease. Researchers from Inserm, CNRS and Université de Paris have shown that the emulsifiers present in many processed foods could have a harmful impact on specific bacteria in the gut microbiota, leading to chronic inflammation.
A study is showing for the first time that tobacco consumption, even when stopped before pregnancy, can have an impact on the placenta. Smoking not just during but also before pregnancy leads to epigenetic modifications (DNA methylation) which could have consequences on its course.