Treating hard and fast seems to be a good way to limit the side effects of radiotherapy. This is the discovery made by researchers at the Curie Institute, Inserm and the Vaud University Hospital, published in Science Translational Medicine on 16 July. Radiotherapy remains one of the benchmark local treatments for cancer patients: increasingly accurate, it consists of irradiating cancer cells to destroy them while preserving neighbouring healthy tissues and...
Under normal conditions and because it cannot store oxygen, the brain cannot withstand being deprived of oxygen for more than a few minutes without risking serious consequences. After an accident (cranial trauma or stroke), emergency teams therefore try to restore cerebral oxygenation as quickly as possible. The faster and more precisely physicians work, the greater the chances of recovery. A multi-disciplinary team at the Grenoble Institute of Neuroscience (GIN,...
The team of Emmanuel Lagarde, research director at Inserm's Research Centre for Epidemiology and Biostatistics (Inserm/University of Bordeaux) has studied the subsequent development of 1,300 people who were admitted to A&R between 2007 and 2009 for trauma.
At the request of the Agence Nationale de Sécurité du Médicament et des produits de santé (ANSM) [French National Agency of Medicine and Health Products Safety], a group of researchers managed by Florent de Vathaire in Inserm Unit 1018 Centre for epidemiology and population health research is launching a study entitled LUCIE.
A new ultrasound imaging technique has provided the first ever in vivo visualization of activity in the piriform cortex of rats during odor perception. This deep-seated brain structure plays an important role in olfaction, and was inaccessible to functional imaging until now. This work also sheds new light on the still poorly known functioning of the olfactory system, and notably how information is processed in the brain.
One of the goals of the laboratory is to develop laser and microfabrication technologies with the aim of printing tissues in vitro and in vivo. The researchers in the laboratory were pioneers in Europe, developing laser-assisted bioprinting from 2005. This Inserm/University of Bordeaux joint research unit is one of a very few worldwide to use this process. The objective of Fabien Guillemot’s team is therefore not only to position...
How many patients receive an incorrect diagnosis of Alzheimer’s disease? The answer is a surprisingly high number: over a third! To reduce the number of errors, the diagnostic criteria must be the most reliable possible, especially at the very early stages of the disease. For the last decade, an international team of neurologists, coordinated by Bruno Dubois (Inserm/Pierre and Marie Curie University/AP-HP Joint Research Unit 975) has been working...
Neurons cannot properly defend themselves against Huntington’s disease, right from the onset of the pathology. This has been discovered by a team of Inserm researchers from the Paris-Seine Biology Institute (IBPS) (Inserm/CNRS/Pierre and Marie Curie University) and their American and Australian colleagues. The cause is the failure of an important mechanism involved in cellular longevity. In addition to this result, the present study shows the importance of restoring the...
Many medical situations require a supply of red blood cells—anaemia, road accidents and chemotherapy, for example. But there is a genuine shortage of blood. Researchers throughout the world are therefore working hard to find solutions to alleviate these shortages, and their sights are set on the potential for creating an unlimited supply of red blood […]
Teams led by Priscille Brodin in Lille and Laurent Marsollier in Angers have studied lesions in patients with Buruli ulcer, a tropical disease.