Certain parts of DNA are highly mobile and their dynamic motion participates in controlling gene expression. The research team working under Maria‐Elena Torres‐Padilla, an Inserm research director at the Institute of Genetics and Molecular and Cellular Biology, has just developed a method of observing the organisation and movements of the genome in time and space.
The impact of depression on a person contracting cancer has long been suspected, without any study having definitely confirmed or rejected this theory. The links have now been investigated by Cédric Lemogne, a member of the team headed by Marie Zins (INSERM’s Mixed Research Unit 1018 “Epidemiology and Population Health Research Centre”, AP-HP, University of Versailles Saint-Quentin), who monitored 14,203 people between 1994 and 2009, including 1119 who developed...
A team of researchers led by Michel De Waard, Inserm Research Director at the Grenoble Institute of Neurosciences (Inserm, University Joseph Fourier, CNRS), has discovered that an African medicinal plant produces large quantities of molecules with analgesic properties.
Inserm researcher Elvire Gouze, and her associates from the Mediterranean Centre for Molecular Medicine in Nice (Inserm Unit 106), have succeeded in restoring bone growth in mice suffering from this developmental pathology.
By means of virtual screening and experiments on mice and human cells in culture, the scientists were able to screen 200,000 compounds and selected two that allowed the causal mutated protein in cystic fibrosis to express itself and fulfill its function.
A l’occasion de la journée mondiale de la maladie d’Alzheimer qui se tiendra le 21 septembre 2013, le service de presse de l’Inserm vous compile les dernières actualités/avancées sur cette maladie.
The European Union commits funds to the FIBRO-TARGETS research consortium
Menée par le Pr Philippe Gabriel Steg, de l'hôpital Bichat, (AP-HP) et l’équipe de recherche affiliée au Département Hospitalo-Universitaire FIRE, à l’Université Paris-Diderot et à l'Unité Inserm U-698, l’étude a porté sur plus de 24 000 patients traités par angioplastie et sur un nouveau traitement antiplaquettaire injectable inhibant la formation des caillots de plaquettes, le cangrelor. Les chercheurs ont analysé la totalité des résultats obtenus avec ce nouveau traitement...
De Tom Simpson à Marco Pantani et Laurent Fignon, de nombreux cyclistes professionnels ont perdu la vie prématurément. Pour autant, depuis plus de 20 ans et dans de nombreuses disciplines, plusieurs études ont montré que les sportifs présentaient une durée de vie supérieure à la moyenne.
The ANRS-12126 “Bophelo Pele” Project implemented in the township of Orange Farm in South Africa has confirmed the effectiveness of a large-scale program of voluntary medical male circumcision in prevention of heterosexually acquired HIV infection. The follow-up of over 3300 men shows a 57% to 61% reduction in the rate of new HIV infections in circumcised men compared with uncircumcised men.
They observed that these individuals were deficient in intestinal bacteria (in both quantity and diversity) and were at greater risk of developing cardio-metabolic diseases.
